Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 141 for “"genetic manipulation"”.
-
Genetic manipulation and human rights
… on the ethical, social and legal aspects of genetic manipulation within the frame of human rights. The thesis tries to dig deep into the process of genetic manipulation and explain how postmodern philosophy of human nature can reflect dangerously on the hardly-gained human rights.
-
Minimizing interference due to genetic manipulation
Synthetic gene networks are the functional genetic 'programs' that will form the basis of increasingly sophisticated engineered organisms, cells and tissues. Important factors to consider in biologically engineering circuits are modularity and orthogonality of the components. We explore these …
-
Genetic Manipulation and Characterization of Solvent-Producing Clostridia
Preliminary work has been done on the formulation of a new solventogenic clostridial fermentation medium based on the use of corn steep liquor (CSL). CSL is a by-product of the corn wet-milling industry, and has been used primarily as a feed supplement in the livestock industry. This nutrient-rich …
-
GENETIC MANIPULATION OF STORAGE ROOT DEVELOPMENT IN HORTICULTURAL CROPS
A novel cdc2-like protein kinase gene (Bvcrkl) has been isolated from sugar beet in the Norman Borlaug Institute laboratories. The expression of this gene is associated with dividing tissue, particularly the secondary vascular cambial rings of the sugar beet storage root. This gene is of interest …
-
GENETIC MANIPULATION OF CYTOKININ LEVELS IN NEW PLANT TYPE RICE
… examined in various parts of NPT rice. A phylogenetic tree showed that the SAG12 gene had homology with several cysteine proteases in cereals, such as, maize, barley and rice and clustered closest to two rice BAC clones, namely, OSM146118 and OSM146316. However, the OSMl46118 rice BAC clone was …
-
Genetic manipulation : the paradox of control in a flexible corporation
… In contrast I find the biological metaphor of genetic manipulation best illustrates the kind of control exercised by the leadership of this particular firm. From its inception, the leadership team wanted to create a flexible firm, one that could thrive in a turbulent environment. Rather than …
-
Genetic Manipulation of Bacteroides for Transient Colonization of Germ-free Mice
… D-Ala. This mutation strategy may be adapted to genetically manipulate other notable Bacteroides species. The generated auxotrophic mutants from this study will be useful tools in answering questions regarding how timing or dosage of bacterial exposure affect health or disease outcomes in …
-
Progenitor cells in the postnatal central nervous system, characterization and genetic manipulation
… they give rise to new interneurons. We have genetically manipulated the postnatal SVZ progenitor cells with the aim to direct them to a neuronal fate in the striatum. Our result showed that ectopic expression of the transcription factors Islet1 and Neurogenin2 directed the SVZ cells progeny …
-
Chemical genetic manipulation of interferon regulatory factor 1 (IRF-1) using synthetic biology
Interferon regulatory factor 1 (IRF-1), the founding member of IRF family, is a nuclear transcription factor first described as a transcription factor that binds to the upstream region of interferon induced genes following viral infection. In addition, IRF-1 has been reported to be involved in cell …
-
Regulating Inflammation Through Exercise-Mediated Trained Immunity or Genetic Manipulation of the Interferon Locus
… factors such as exercise and 2) by genetically manipulating or pharmaceutically targeting key immune modulatory factors, such as interferons. In my thesis, I employed both approaches. First, we explored whether exercise training could induce adaptations in bone marrow-derived …
-
Molecular genetic manipulation and characterization of the high-potential chain of cyclic electron transport in Rhodobacter sphaeroides
The Rieske iron-sulfur subunit of the cytochrome bc$\sb{1}$ complex of Rhodobacter sphaeroides assembles in the E. coli and R. sphaerodies membranes with its iron-sulfur cluster intact, in the absence of the cytochrome subunits. This assembly, in light of predicted structural features of the …
-
Development and application of machine learning tools for the advancement of energy crop genetic manipulation using the CRISPR/Cas technology
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01
-
Novel High-throughput Technologies for Applications in Microbiology
… dependent, hindering the progress of bacterial genetic engineering. To address these challenges, this study focuses on developing high-throughput solutions to streamline the process, improve efficiency, and ensure consistent results. The primary contribution of this research is the development …
-
Development of a transformation protocol and cell culture system for the commercially important species of red macroalga, Gracilaria gracilis
… commercially important seaweed responds at a genetic level to stresses faced in the aquaculture environment would not only be advantageous to the South African industry, but this knowledge is essential for selecting and/or engineering macroalgal strains that are either more tolerant or …
-
Identification of novel gastric stem cell markers and investigation of Intestinal Stem Cell Cre-mediated Recombination
<p>Very few genetic markers for gastric stem cells are currently described. Identifying new markers is important for increasing our basic understanding of gastric tissues and studying mechanisms of cancer development. Gastric and intestinal tissues share a common developmental program. Thus, …
Page 1 of 8