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Showing 1 to 2 of 2 for “"genetic immunity"”.

  1. Monogenic Defects of the Type I Interferons Signaling Pathway in Humans: Molecular and Clinical Implications

    … have reinvigorated the study of the human genetic basis of infectious disease. This theory, so far demonstrated for a number of bacterial, fungal, and viral infections, holds that germs are a necessary but not sufficient condition for infectious disease with susceptibility determined by the …

    rockefeller Repository record for Monogenic Defects of the Type I Interferons Signaling Pathway in Humans: Molecular and Clinical Implications (opens in a new tab)

  2. INVESTIGATING IMMUNE SYSTEM REGULATION THROUGH CROSS-DISEASE GENETIC ANALYSIS AND B CELL FATE DECISIONS

    … cluster into families, suggesting a shared genetic mechanism. Common genetic causes might indicate shared pathogenic mechanisms that cross-disease therapies could target. In this thesis, I investigated the genetic relationship among nine immune-mediated diseases. I identified three different …

    milano Repository record for INVESTIGATING IMMUNE SYSTEM REGULATION THROUGH CROSS-DISEASE GENETIC ANALYSIS AND B CELL FATE DECISIONS (opens in a new tab)