Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 16 of 16 for “"genetic effect"”.
-
Genetic Effect of ALOX15 Polymorphisms on Aspirin-Exacerbated Respiratory Disease
… respiratory disease (AERD). To investigate genetic contribution of ALOX15 in the development of AERD, we performed the genetic association of ALOX15 study in a Korean population. MATERIALS AND METHODS: One hundred-seventy one patients with AERD, 229 patients with aspirin-tolerant asthma …
-
Genetic Effect of MBL2 Polymorphisms in Patients with Diisocyanate-induced Occupational Asthma
… MATERIALS AND METHODS: To demonstrate genetic association of MBL2 polymorphisms in DI-OA, 99 patients with DI-OA, 99 asymptomatic exposed controls (AEC) and 144 unexposed normal controls were enrolled. Three polymorphisms (-554 G>C, -431 A>C and -225 G>C) in the MBL2 promoter were …
-
Genetic effect of histamine N-methyltransferase (HNMT) polymorphism on chronic urticaria with aspirin hypersensitivity
… oxidase (DAO). Especially, the presence of HNMT genetic polymorphisms might results in reduced histamine metabolism and may influence the susceptibility to develop chronic urticaria with aspirin hypersensitivity. This study investigated the histamine metabolism related gene and functional …
-
Japanese courage: a genetic analysis of complex traits in medaka fish and humans
… characteristics relevant to its utility for the genetic mapping of complex traits, including: the panel's evolutionary relationship with other previously-established inbred medaka strains; the degree of homozygosity in the inbred lines; the rate of linkage disequilibrium decay across the panel; …
-
Associations between traits (blood pressure and body height growth) and reproductive timing related genetic variants from genome-wide association studies
… studies (GWAS) have identified many common genetic variants that are associated with women’s reproductive timing characteristics including ages at menarche and at natural menopause. However, the associations of these variants with other human health related phenotypes such as blood pressure, …
-
The Distribution of Genetic Variation Among Relictual Populations of Missouri Tallgrass Prairie Plants
The amount of genetic variability that is lost from a species when an ecosystem is fragmented will be proportional to the magnitude of genetic differentiation among its individual populations. To assess the genetic effect of habitat destruction on tallgrass prairie plant species, Wright's …
-
Genetics of Experience: Genetically Sensitive Approaches to Measuring Childhood Environment
Environmental experience is not free of genetic influence. Through genetically-influenced behaviours, genes can influence exposure to certain environments: gene-environment correlation. Particular genotypes may also be more or less sensitive to the effects of the environment: gene-environment …
-
Evaluation of feedlot feed efficiency relationships as well as genetic and phenotypic performance, carcass, and economic outcomes
… dissertation was to investigate: 1) heterosis effects on feed efficiency, 2) how measures of feed efficiency affect one another, 3) heritability estimates, 4) genetic and phenotypic relationships of performance, carcass, economic, and feed efficiency traits and 5) the relationship of economic …
-
Nervous system cancer : analysis of historical mortality rates in the United States and Japan indicate sudden increases in environmental risk
… only be caused by two factors, environmental and genetic effects. Given the suddenness of the change in NS cancer mortality rates, we can rule out the contribution of a possible genetic effect and focus on characterizing a possible environmental risk factor. Herein the possibility of …
-
The Genetic Architecture of Grain Quality and its Temporal Relationship with Growth and Development in Winter Malting Barley (Hordeum vulgare)
This thesis explores the genetic architecture of malting quality within the Virginia Tech barley breeding program, and discusses implications for imposing selection on complex traits that are difficult to phenotype. Malting quality measures are destructive, and can not be performed before selection …
-
Hereditary risk factors for stroke in humans - Association studies with emphasis on familial and genotypic factors
… The aim of this thesis was to assess possible genetic impact on stroke risk. We thus evaluated family history of stroke-related individual traits as well as allelic variations in selected candidate genes. Methods Association studies, primarily of Lund Stroke Register data, were fundamentals in …
-
Pharmacogenetic markers of response to drugs used in the management of Inflammatory Bowel Disease
… to those affected. Immunosuppression in IBD is effective but limited by side effects and non-response. We aimed to identify pharmacogenetic markers of response to commonly used immunosuppressive medication in these patients.<br/>Methods: The influence of MTHFR 677C>T, MTHFR 1298A>T, ATIC 347C>G, …
-
Soluble carbohydrates in soybean - discovery of novel genetic resources and evaluation of known mutations
… topics, including i) the identification of novel genetic resources for high sucrose and low stachyose content via genome-wide association study (GWAS), ii) the discovery of novel quantitative trait loci (QTL) and variants for high sucrose content via QTL mapping, and iii) the evaluation of …
-
A genetic analysis of molecular traits in skeletal muscle
… of molecular quantitative trait loci (QTLs), genetic associations with molecular traits such as gene expression (eQTLs) and DNA methylation (mQTLs). The Finland-United States Investigation of NIDDM (FUSION) tissue biopsy study is motivated by the desire to understand the molecular pathogenesis …
-
Genetics, humoral immunoresponsiveness, and disease resistance in chickens
… SRBC were similar for both lines suggesting that genetic factors that influence primary and memory responses are not the same. The responses of LA chicks to repeat inoculations with SRBC were anamnestic whereas those of HA chicks initially inoculated at 28 days of age were not anamnestic. This …
-
Effect of pulmonary arterial pressure and precipitation on reproductive performance in Angus heifers in south central Wyoming
… on snowmelt. This variable water availability effects forage production and nutrient availability for developing heifers relying on forage resources. Due to this, precipitation amount is of concern to beef producers. Furthermore, in areas of the mountain west above 1,500 meters, producers have …