Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 10454 for “"genes"”.
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Control of late genes, early genes, the cI gene, and replication in bacteriophage [lambda]
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1971.
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Xenobiotic Metabolism Genes and Clubfoot
… that genetic variation in smoking metabolism genes may increase susceptibility to clubfoot. Based on this reasoning, we interrogated eight candidate genes, chosen based on their involvement in phase 1 and 2 cigarette smoke metabolism. Twenty-two SNPs and two null alleles in eight genes …
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Pyrimidine Genes in Pseudomonas Species
… Pseudomonas. Pyrimidine biosynthesis and salvage genes will be aligned for P. aeruginosa PAO1, P. putida KT2440, and P. syringae DC3000. The whole study will gives insight into gene patterns in Pseudomonas, with a focus on pyrimidine genes.
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Proneural Genes in Neocortical Development
… is regulated by both intrinsic proneural genes Neurog2 and Ascl1, and extrinsic signals. However, how these intrinsic factors and extrinsic signals coordinatedly control neural cell fate decisions was not well understood at the start of my studies. Neurog2 and Ascl1 were known to be …
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Fusion genes in breast cancer
Fusion genes caused by chromosomal rearrangements are a common and important feature in haematological malignancies, but have until recently been seen as unimportant in epithelial cancers. The discovery of recurrent fusion genes in prostate and lung cancer suggests that fusion genes may play an …
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Detection of virulence genes and antimicrobial resistance genes in staphylococci isolated at Malamulo hospital in Malawi.
… aimed at detecting selected virulence and AMR genes in 36 Staphylococci bacteria stocked between December 2021 and May 2022 for a molecular AMR surveillance. Sample source types included blood (16), urine (14), pus (three), skin wedge (one), pleural fluid (one), and ascitic fluid (one). …
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Detection of virulence genes and antimicrobial resistance genes in staphylococci isolated at Malamulo hospital in Malawi.
… aimed at detecting selected virulence and AMR genes in 36 Staphylococci bacteria stocked between December 2021 and May 2022 for a molecular AMR surveillance. Sample source types included blood (16), urine (14), pus (three), skin wedge (one), pleural fluid (one), and ascitic fluid (one). …
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RNAi-related genes in Toxoplasma gondii.
RNA interference (RNAi) is an evolutionarily conserved mechanism through which double-stranded RNA (dsRNA) triggers degradation of homologous transcripts. Argonaute proteins and small interfering RNAs (siRNAs) are the known signature components of the RNAi effector complex, named RNA-induced …
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Expression Of Growth Factor Inducible Genes
… cDNA clones for the growth factor inducible genes TIMP, MRP, MEP and calcyclin were isolated, and used to study the temporal and spatial patterns of expression of these genes. The TIMP and MRP cDNAs were used to express the murine proteins in E. coli. The native proteins were found to be …
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Transcription of human-specific duplicate genes
In this work, I set out to characterize new genes contained specifically within the human genome but absent from any other, including our closest evolutionary cousins. Our interest in these genes is twofold: First, gene duplication is a fundamental process by which evolutionary innovations at the …
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ETHANOL REGULATION OF GLUCOCORTICOID RESPONSIVE GENES
… was accompanied by a highly correlated group of genes, many of which are also known to respond to glucocorticoids. This suggests that stress-related signaling events might play an important role in ethanol regulation of the Sgk1 gene network. Prior work by others showed that Sgk1 plays an …
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Candidate Genes for Late Diabetic Complications
… factors are believed to play role in pathogenesis of diabetic complications. The aim of this study was to 1) To test the usefulness of the new WHO criteria for clinical staging of diabetes in the characterization of diabetic patients. 2) To test a putative association between late diabetic …
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Functional analysis of plastid-encoded genes
… which most probably represent functional genes. The primary aim of this thesis was the analysis of the role of two such ORFs, designated ycfs or hypothetical chloroplast reading frames, namely ycf9 (ORF62) and ycf10 (ORF229, cemA). Both were analyzed in Nicotiana tabacum (tobacco) via …
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Large Artery Stiffness: Genes and Pathways
… and aortic aneurysms and is linked to the pathogenesis of cognitive impairment, stroke and renal failure. Like most cardiovascular traits, aortic stiffness is a complex trait and is moderately heritable, yet the precise molecular mechanisms that underpin the stiffening process remain poorly …
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Oxygen Regulated Genes in Salmonella Typhimurium
Studies on oxd-2 showed that it encodes a 42-kD protein which has acetate/propionate kinase activities. The cloned oxd-2 gene, under a foreign promoter, complemented an ackA (encoding an acetate kinase) mutation. Both Oxd-2 and AckA have a similar substrate range, and Oxd-2 has higher affinity for …
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Functional analysis of soybean dirigent genes
… project, the expression of the soybean dirigent genes and their effect on plant defense to pathogens was studied. Dirigent proteins, present in all of the major land plants, have been hypothesized to work in concert with oxidative enzymes to direct the synthesis of stereospecific lignans, such as …
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Differentially expressed genes in oesophageal cancer
… instability of clonal evolution. Several oncogenes, tumour suppressor genes and transcription factors have been shown to be altered in oesophageal cancer. Their role however, in the development and/or susceptibility to the development of oesophageal cancer is poorly understood. The aim if this …
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Computational comparative genomics : genes, regulation, evolution
… contains the blueprint of all protein-coding genes and the regulatory motifs used to coordinate the expression of these genes. Comparative genome analysis of related species provides a general approach for identifying these functional elements, by virtue of their stronger conservation across …
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Mosquito Transposable Elements and piwi Genes
… in assisting the spread of disease-resistant genes in mosquito populations. This research focuses on two related subjects, TEs and their regulation. The first subject is on a Long Terminal Repeat (LTR) retrotransposon in the African malaria mosquito, Anopheles gambiae, namely Belly. The second …
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