Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"gene validation"”.
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Understanding the neuroadaptations underlying the effects of (+)-methylenedioxymethamphetamine [(+)-MDMA; ecstasy]: Implications for the serotonin 5-HT2A receptor and its binding partners
Repeated administration of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) induces “behavioral sensitization,” an enhancement of its behavioral effects. The molecular changes underlying behavioral sensitization may be linked to neuropsychological sequelae (e.g., depression, anxiety) seen upon …
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HSP70: a therapeutic biomarker for treatment of glioma
… Dnmt3a, Alcam, Cdk4, Dnajc16 (Hsp40) and R-Ras2 genes, respectively. Gene validation using qRT-PCR suggested no correlation between miRNA-mRNA levels, and thus, challenges the suitability of miRNAs technology as treatment predictors. In conclusion, the result for the protein data showed that …
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Can curcumin improve the methotrexate based treatment for rheumatoid arthritis?
… effectively used as stability indicating method. Gene expression profiling was performed using HFLS-RA cells treated with MTX and curcumin separately and concurrently. The DNA microarray data identified 53 genes that were downregulated and 21 genes that were upregulated in all the treated samples …
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A Genomic Approach to Identify The Notch Pathway As A Putative Tumor Suppressor In Endometrial Cancer
… We validated the differential expression of ten genes whose expression was significantly up-regulated or down-regulated using qRT-PCR. All of the genes had distinct expression levels depending on the endometrial carcinoma histotype. As a result, they could serve as molecular markers to …