Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 206 for “"gene family"”.
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The AtMRS2 gene family from Arabidopsis thaliana
… laboratory) identified an Arabidopsis thaliana gene by the complementation of a Mg2+-uptake yeast mutant (CM66). This gene, referred to as AtMRS2-11, was expressed as cDNA from a strong yeast promoter and allowed the growth of the CM66 yeast strain on standard media. The conceptually translated …
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Evolutionary Dynamics of the Alpha-actinin Gene Family
The alpha-actinin gene family is a member of the spectrin superfamily of proteins. Other members of this superfamily include the a- and ~-spectrins, ~heavy spectrin and dystrophin. Each member of this superfamily has a unique actin cross-linking distance consequent to the specific number of …
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The polygalacturonase-encoding gene family of Aspergillus niger
Contains fulltext : mmubn000001_14818264x.pdf (Publisher’s version ) (Open Access)
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Functional analysis of the CP12 gene family in Arabidopsis
… intensity. In Arabidopsis, there are three CP12 genes, CP12-1, CP12-2 and CP12-3. Expression analysis of these genes suggested that they may have a wider role in non-photosynthetic plastids through the plants’ life cycle and that their function may not be restricted to the Calvin-Benson cycle. …
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The retinoblastoma gene family in tumor suppression and development
… important roles in the regulation of both tumorigenesis and tissue-specific differentiation. To determine the role of Rb in development more precisely, we analyzed chimeric embryos and adults made with marked Rb-/- cells. We demonstrated that although brains of chimeric embryos exhibited …
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Characterization of The Ato Gene Family In Alternative Carbon Metabolism
… revealing an overlapping set of up-regulated genes, including several members of the poorly understood <em>ATO </em>family. This family is greatly expanded in <em>C. albicans </em>relative to other fungi and has been implicated in both ammonia release (Ammonia Transport Outward) and acetate …
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Spatial Expression Patterns of theSnmp Gene Family In Drosophila Melanogaster
… SNMP1 as well as SNMP2. Via the GAL4-UAS transgenesis system in tandem with immunohistochemical methods, we show that SNMP1 expresses in neural and support cells of the antennae as is consistent with the aforementioned studies. However, it is also shown that SNMP1 expression is not limited to …
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Characterization of a Putative Activation Domain in the Hulk Gene Family
The HULK gene family participates in regulation of both flowering time and development in the plant Arabidopsis thaliana. The proteins encoded by these genes share conserved domain structures including a proline-rich region (PRR) in the carboxyl-terminus. Based on sequence analysis and the presence …
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Identification of Cyclophilin gene family in soybean and characterization of GmCYP1
I identified members of the Cyclophilin (CYP) gene family in soybean (Glycine max) and characterized the GmCYP1, one of the members of soybean CYP. CYPs belong to the immunophilin superfamily with peptidyl-prolyl cis-trans isomerase (PPIase) activity. PPIase catalyzes the interconversion of the …
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Functional analysis of the sucrose synthase gene family in Arabidopsis thaliana
… was investigated using promoter-reporter gene constructs (GUS) and real time RT-PCR. Although these isoforms are closely related at the protein level they have radically different spatial and temporal patterns of expression in the plant with no two isoforms showing the same distribution. …
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The human Deleted in Azoospermia gene family : structure, function and evolution
The human Deleted in Azoospermia genes lie within the AZFc region of the Y chromosome that is frequently deleted in men with severe spermatogenic failure and male infertility. This thesis describes the evolution, structure and function of human DAZ genes. First, we determined that Y-linked DAZ …
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The cloning and characterisation of the chicken tyrosinase-related protein gene family
Very little is known about the molecular and genetic mechanisms controlling pigmentation within the bird kingdom. The aim therefore, of this study was to contribute towards the understanding of the genetic regulation of avian pigmentation by the cloning and characterisation of the chicken …
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Methods and analysis of genome-scale gene family evolution across multiple species
… datasets. In this work, I explore how evolution generates the diversity of life we see in modern species, specifically the evolution of new genes and functions. By reconstructing the history of the diverse sequences present in modern species, we can improve our understanding of their function and …
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Identification of pyruvate decarboxylase/indole pyruvate decarboxylase gene family members from Arabidopsis thaliana.
… Six putative Arabidopsis thaliana PDC gene family members have been individually cloned and expressed in E. coli, and recombinant PDC proteins were purified and biochemically characterized. AtPDC2 was identified as a unique functional PDC based on its measured biochemical activity. The …
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Bioinformatics Investigation on the Role of Obox Gene Family in Preimplantation Embryo Development
… using mainly the mouse as a model organism, the gene regulatory mechanisms are still not well understood. The next-generation sequencing technologies enable researchers to obtain the genome-wide expression profiling with single-cell resolution, which are powerful tools to study early …
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The Intricate Molecular Landscape of Insect Chemosensation: The Sensory Neuron Membrane Protein Gene Family
… Neuron Membrane Proteins) are members of a gene family characterized by human CD36. This family has diverse functions including transportation of fatty acids and interactions with other proteins in cell:cell recognition. SNMPs are membrane proteins observed to associate with chemosensory …
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A role for the Speedy gene family in the early stages of mammalian meiosis
… result is the formation of haploid gametes. The genes and signals that regulate the decision to enter meiosis are not entirely elucidated in mammals. I hypothesize that the Speedy/RINGO gene family functions endogenously in the early stages of meiosis including: meiotic initiation, premeiotic DNA …
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