Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 37 for “"gastrointestinal disease"”.
-
Noncanonical NF-KB in Gastrointestinal Disease
… NF-KB to inflammatory and neoplastic disease in the gastrointestinal (GI) system, as well as the effects of its loss on GI health. Chapter 1 opens with an overview of gastrointestinal homeostasis and inflammation, with emphasis on the particular diseases studied in this body of work. …
-
Novel insights into the inflammatory basis of gastrointestinal disease
… strong, the health of the host is damaged and disease can occur. The implication of intestinal disease caused by an ineffective immune response is of great social and economic burden to society. The overarching purpose of this thesis is to assess inflammatory signalling targets associated with …
-
Factors influencing development and outcome of equine gastrointestinal disease
Gastrointestinal diseases are a common cause of morbidity and mortality in horses. Colic refers to clinical signs attributed to abdominal pain in horses. The pathology underlying colic is diverse, which makes accurate prediction of survival challenging. Equine Gastric Ulcer Syndrome (EGUS) is …
-
Detection of apoptotic cells in horses with and without gastrointestinal disease
… if the occurrence of apoptosis is affected by gastrointestinal disease and tissue layer of intestine. Samples of intestine were collected from 38 horses that underwent surgery or were humanely destroyed for small or large bowel obstruction, strangulation or distension. Samples were also taken …
-
The Relationship Between Gastrointestinal Disease and Post-traumatic Stress Disorder in United States Military Veterans
This study examined relationship between gastrointestinal disease (GI Disease) and post-traumatic stress disorder (PTSD) in United States Military Veterans. Based upon literature and clinical practice data sources from the US Veterans Administration, GI disease and PTSD were hypothesized to be …
-
New approaches to culture and detection of verocytotoxin producing escherichia coli (VTEC) in clinical laboratory diagnosis
… of faeeal specimens collected from cases of gastrointestinal disease in the North West of England was undertaken using the developed methods. Evidence of VTEC was found in 1.6-2.6% of the specimens tested and this detection rate was found to be similar to those of other European countries and …
-
Factors and Mechanisms Involved in Epithelial Injury and Repair of Equine Colon
… be beneficial in the treatment of horses with gastrointestinal disease. The increase of mucosal permeability caused by acetylcysteine may be caused by the mucolytic properties of acetylcysteine. A lower dose may prevent mucolysis while allowing for the beneficial effects of acetylcysteine. …
-
Immune and allergic responses to Anisakis pegreffii, with focus on the roles of IL-4, IL-13 and the IL-4 receptor alpha
… nematode Anisakis pegreffii induces gastrointestinal disease and allergy when ingested by humans, and can cause occupational allergy in seafood processing workers. The present study examines immune and allergic responses to A. pegreffii in wildtype and gene deficient mice, with …
-
Posterior Laryngitis- Aetiology,Treatment and Health-Related Quality of Life
… levels, and symptoms associated with functional gastrointestinal disease. Their HRQOL was registered before and after treatment. In paper III, patients with PL were scrutinized for the presence of gonadotropin-releasing hormone (GnRH) antibodies. In paper IV, patients with diabetes mellitus were …
-
An audit of patients undergoing gastroscopy at Mitchells Plain District Hospital, with a focus on substance use
… is largely unexplained. Locally, the pattern of gastrointestinal disease among methamphetamine users, as well as the manner in which they present, remains poorly understood. With an increase in the use of methamphetamine globally, a better understanding of the gastrointestinal effects of this …
-
Experimental studies of RctB- initiator of Vibrio cholerae chromosome II replication: genetic engineering, protein purification, and protein crystals
… is notorious as the causative agent of acute gastrointestinal disease known as cholera. Genetic information in members of the Vibrionaceae family is distributed between two chromosomes that are distinctively maintained. In V. cholerae, the initiation of DNA replication in each chromosome …
-
Elucidation of an oral drug delivery mechanism to the mammalian gastrointestinal tract via an engineered T4 phage
Current treatments of gastrointestinal (gut) disease are limited by high dosing frequency, patient noncompliance, and complications circumventing the harsh conditions of the upper gastrointestinal tract (e.g. stomach), leading to therapeutic degradation. Bacterial cells were previously explored as …
-
Expression of the Human Milk Protein, Beta-Casein : in Transgenic Potato Plants
… proteins in cow milk were responsible for gastrointestinal disease and even digestive collapse of the newborn fed a cow milk-based diet<sup>16</sup>. The allergenicity of cow milk for the human infant appears to be caused predominantly by p-casein<sup>17</sup>. In this research, the cDNA …
-
Genetic technologies to engineer and understand the microbiome
… the human body are integral to human health and disease: from inflammatory bowel disease to allergy, metabolic syndrome to autism. Due to its high connectivity with human physiology, manipulation of the microbiota has therapeutic potential in a vast array of diseases. However, techniques for …
-
Inactivation of adenovirus serotype 41 with monochloramine
… die worldwide each day because of preventable diseases caused by a lack of safe water and sanitation. Human Adenovirus (HAdV) is a viral pathogen that persists in contaminated water and is commonly found to cause diarrhea worldwide. The United States Environmental Protection Agency has included …
-
Molecular and genetic analysis of Cryptosporidium spp. oocysts : sources and genotypes in the environment
… parvum is responsible for an acute gastrointestinal disease that is self-limiting in immunocompetent people but potentially life-threatening for the immunocompromised. Until recently, C. parvum was the only species of Cryptosporidium known to cause disease in people, however, reports …
-
Evaluation of a Paratuberculosis Quantitative Polymerase Chain Reaction Assay with Microscopic Correlation
… paratuberculosis (MAP) and precedes Johne's disease, a chronic enteric disorder in ruminants caused by MAP infection. Necropsy with histopathology provides definitive diagnosis of Johne's disease and positive culture of MAP from tissues provides definitive diagnosis of paratuberculosis. To …
-
Study of the Cryptosporidium parvum DHFR-TS in the model system Saccharomyces cerevisiae
… is a ubiquitous protozoan that causes severe gastrointestinal disease. The severe diarrhea that results can be life-threatening, particularly for the very young, old, and immune-compromised. Currently there is no approved therapy for cryptosporidiosis. We have developed a method using the …
-
Cardiac arrest in children preceding PICU admission: Aetiology and outcome in a developing country
… - 21.6) months; 30.8% had chronic underlying disease. Children presented most commonly with respiratory (n=28, 27.2%), cardiovascular (n= 22, 21.4%), and gastrointestinal disease (n= 20, 19.4%). Twenty-eight (27.2%) arrested while undergoing a procedure. Cardiopulmonary resuscitation (CPR) was …
Page 1 of 2