Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"gastric tumor"”.
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DISSECTING THE ROLE OF Β-CATENIN AND MYC IN GASTRIC TUMOR FORMATION
… in the vast majority of human gastrointestinal tumors. Despite it is well known that deregulation of Wnt signaling pathway is a clear genetic event driving the onset of intestinal tumors, its role in gastric tumorigenesis remains elusive. Here, using conditional transgenic mouse models, we show …
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Regulation of RUNX3 in gastric and breast cancer
… been acknowledged that RUNX3 is involved as a tumor suppressor in many distinct cancers in different tissues. In this thesis, we will examine the regulation of this tumor suppressor in gastric cancer and breast cancer. Chronic infection with cagA-positive Helicobacter pylori is the strongest …
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Regulatory CD4+FOXP3+ T cells in Helicobacter pylori-induced disease
Helicobacter pylori colonize the gastric or duodenal mucosa of approximately half of the worlds’ population. Although most individuals are asymptomatic, H. pylori infection cause peptic ulcers or gastric cancer in 10-15 % and 1-2 %, respectively, of the infected individuals. It has previously been …
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The Recruitment and Function of Tumor Microenvironment Components During Gastric Carcinogenesis
… used for numerous years as a standard model of gastric carcinogenesis and recapitulates the pathogenesis seen with human Helicobacter pylori infection. H. felis induces a a wide array of chronic low grade inflammatory responses, some of which directly contribute to carcinogenesis and some of …