Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 98 for “"gastric cancer"”.
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Pharmacology of gastric cancer chemotherapy
… pharmacotherapies and other therapies of gastric cancer
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Carbonate Ions and Gastric Cancer
Nearly one million new cases of gastric cancer are diagnosed annually throughout the world. Even though the incidence has fallen dramatically in recent decades, this disease is still the second leading cause of cancer death in a global perspective. The geographic distribution of gastric cancer …
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Operative Risk Factors in Gastric Cancer Surgery for Elderly Patients
Purpose: Gastric cancer surgery is popular operation in East Asia like Korea and Japan. Recently, population of elderly has been significantly increased. As results, surgery for gastric cancer surgery for elderly will be also increased. We evaluated the effect of old age on gastric cancer surgery, …
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The effect of gender on Helicobacter pylori and gastric cancer
Gastric cancer is the 2nd leading cause of cancer death worldwide and the 4th most commonly diagnosed cancer worldwide. Helicobacter pylori infection is the major risk factor of gastric cancer, and as such, this bacterium has been classified as a type 1, or definite, carcinogen by the International …
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Genomic Discovery of recurrent CD44-SLC1A2 Gene Fusion in Gastric Cancer
… various genomic abnormalities associated with cancers, fusion genes and transcripts are particularly notable due to their cancer-specific nature and translational potential as diagnostic and therapeutic targets. While fusion genes are well-known in haematological malignancies, our knowledge of …
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EBV-Associated Gastric Cancer: From Initial Infection to Unique Therapeutic Approaches
… EBV is the causative agent of several cancers including lymphomas and epithelial cancers. Specifically, gastric carcinoma, nasopharyngeal carcinoma, and lymphoepithelioma-like carcinoma which occurs across multiple sites in the body, most notably, in the lung. EBV-associated gastric …
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Clinicopathologic Features of the Superficial Spreading Type of Early Gastric Cancer
"-국문요약- 표층팽창형 조기위암의 임상병리학적 특징 서론 최근 진단방법의 발달과 건강 검진의 활성화에 힘입어 조기위암의 발견이 증가되는 추세이다. 하지만 조기위암 환자가 증가하면서 일반적으로 알려진 임상병리적 특징과 달리 넓은 병변을 가지고 있으며 림프절 전이가 잦은 특성을 보이는 조기위암군이 발견되었다. 이런 군을 1942년 Stout가 표층팽창형군으로 분류하였으나 현재까지도 적은 발생율에 의해 정확한 임상병리적 특성은 밝혀지지 않고 있는 상황이다. 이에 이번 연구를 통해 표층팽창형 조기위암의 임상병리학적 특징에 대해 밝혀보고 …
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Genomic Analysis of Chemo-Resistance to HDAC inhibitor in Gastric Cancer cells
… inhibitors (HDACis) are a promising class of anticancer epigenetic drugs, however, molecular factors influencing the responses of individual tumors to HDACi therapies remain obscure. Here, we sought to identify genes associated with HDACi resistance in gastric cancer. Treating a panel of 17 …
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Does the Timing of Adjuvant Chemotherapy for Gastric Cancer Influence Patient Outcome?
… as standard treatment in stage II/III gastric cancer, there is no report about the optimal timing of the initiation of chemotherapy. We investigated the effect of the interval between surgery and the start of chemotherapy on patient outcome. Patients and METHODS: A retrospective review …
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Mechanisms Underlying The Sensitivity and Resistance of Gastric Cancer Cells to Met Inhibitors
… credentialed as a therapeutic target in gastric cancer, but the molecular mechanisms underlying sensitivity and resistance to MET inhibitors are still not well understood. Using whole-genome mRNA expression profiling, we identified autophagy as a top molecular pathway that was activated …
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conventional cytology is not beneficial for prediciting peritoneal recurrence after curative surgery for gastric cancer
… determining further treatment strategies after gastric cancer surgery is still unclear. One reason for this is that optimal procedures to increase the accuracy of predicting peritoneal metastasis have not been established. The aim of this study was to evaluate the efficacy of cytology using …
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COFFEE AND TEA CONSUMPTION AND GASTRIC CANCER: A POOLED ANALYSIS IN AN INTERNATIONAL CONSORTIUM OF EPIDEMIOLOGICAL STUDIES.
… examine the effect of coffee and tea drinking on gastric (stomach) cancer risk. Coffee and tea are among the most popular drinks worldwide after water, and their consumption is expected to rise by an average of 17% over the next several years. The World Cancer Research Fund and the American …
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Oesophago-gastric cancer: factors influencing presentation and the effects of antisecretory drug therapy on symptoms and diagnosis
INTRODUCTION: Upper GI cancer in the UK is associated with a poor prognosis. This thesis was concerned with clarifying the reasons for this, including delays in the diagnosis and the effect of antisecretory drug therapy (AST).
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Clinicopathologic Analysis of Remnant Gastric Cancer after Distal Partial Gastrectomy: Experience of Single Center during 15 years
잔위암은 일반적으로 잔위 주변 임파선전이가 많고 주위조직의 침윤이 많은 것으로 알려져 있다. 14년동안 한 기관에서 수술한 잔위암 환자의 임상병리적 결과에대한 수술적 결과를 후향적으로 연구해보았다. 34명의 환자가 잔위암으로 진단되어 평가에 포함되었다. 잔위암의 과거수술방법에 따른 수술적 결과와 임상병리적 양상을 분석하였다. 34명중 14명은 과거에 암으로 인해 20명은 양성질환으로 위부분절제술을 받은 경우였다. 과거 악성질환으로 수술받은 환자의 경우 처음수술과 잔위암수술의 기간이 양성인 경우와 비교하여 유의하게 짧았다. …
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Molecular Signatures of gastric cancer: An integrated approach to molecular cytogenetics, whole genome copy number and transcriptome profiles
Signature chromosomal translocations in gastric cancer are poorly described. By integrating spectral karyotype and high-resolution genome copy number data, 45 recurrent translocations in 17 human gastric cancer cell lines were identified. Dissecting a simple rearrangement in SNU-1 cells using …
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Expression of Bax Predicts Outcome in Advanced Gastric Cancer Patients Treated With 5-fluorouracil and Platinum Palliative Chemotherapy
… on clinical outcomes in patients with advanced gastric cancer treated with 5-fluorouracil (5-FU) and platinum palliative chemotherapy. Materials and Methods: One hundred and twenty-eight patients with metastatic or recurrent gastric cancer were treated with a chemotherapy regimen of either 5-FU …
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