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Showing 1 to 2 of 2 for “"gamma-carboxylation"”.
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Characterization of Post-translational Modifications and Resulting Structure/Function Relationships of Recombinant Human Factor IX Produced in the Milk of Transgenic Pigs
… modifications (PTMs), including gamma-carboxylation, proteolytic maturation, phosphorylation, sulfation, and glycosylation. Of these PTMs, those known to be vital for activity are gamma-carboxylation of multiple glutamate residues near the N-terminus and proteolytic cleavage of …
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Molekulare Ursachen Vitamin K-abhängiger Gerinnungsstörungen
… essentieller Cofaktor für die posttranslationale Gamma-Carboxylierung von sog. Vitamin K-abhängigen Gerinnungsfaktoren, Knochenproteinen, Zellwachstum-regulierenden und weiteren Proteinen mit noch unbekannter Funktion. Defekte im Vitamin K-Stoffwechsel führen einerseits zu zwei verschiedenen …