Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"gamma delta T cell"”.
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SKIN COMMENSAL STAPHYLOCOCCUS PROMOTES SYSTEMIC V-GAMMA-6 GAMMA-DELTA T CELL RECONFIGURATION
… a robust expansion of IL-17A-producing Vγ6⁺ γδT cells both locally in the dermis and systemically in lymphoid, mucosal, metabolic and central nervous system tissues. This systemic reconfiguration is IL-1R-dependent but independent of IL-23 receptor signaling and the endogenous microbiota. …
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Assessment of Gamma/Delta T Cell Functionality Following Pathogenic HIV/SIV and Non-Pathogenic SIV Infections
… and dysfunction in numerous immunologic cells (including gamma/delta (gamma delta ) T cells) leading to opportunistic infections. gamma delta T cells bridge the innate and adaptive immune responses primarily via cytokines produced in response to microbial phosphoantigens. gamma delta T …
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Discerning the Mechanism of Gamma Delta T Cell-Mediated Damage in Multiple Sclerosis: the Potential Role of Antibodies in Disease Pathogenesis
… in elucidating the role of the innate γδ T-cell population in MS pathogenesis. In particular, some γδ T-cells that express Fc receptors (FcR), such as CD16, that bind antibody are more prominent with MS disease progression and have been shown to exert cytolysis via antibody-dependent …
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The Role of Id Proteins in the Development and Function of T and B Lymphocytes
… thesis, I focused my study on the role of Id2 in gamma delta T cells and CD4<super>+</super> alpha beta T cells, as well as the role of Id3 in B cells.</p><p> Id proteins have been shown to control gamma delta T cell development. Id3 knockout mice demonstrate a dramatic expansion of innate-like …
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Decoding Human T Cell Immunity With Single-Cell Multi-Omics
… I explore human adaptive immunity through single-cell omics by jointly analysing T cell gene expression and T cell receptor (TCR) sequence modalities. Across several longitudinal infectious disease studies, I identify transient T cell states after infection and link these phenotypes with specific …