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Showing 1 to 8 of 8 for “"gabapentinoids"”.
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Factors associated with co-prescription of opioids and gabapentinoids
… with opioids. The rates of prescribing gabapentinoids have significantly increased over the last decade. However, limited research has investigated the impact of excessive prescribing, and the factors associated with the co-prescribing of opioids and gabapentinoids are …
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COMPARATIVE EFFECTS OF GABAPENTINOIDS VS OPIOIDS ON FRAILTY AND PHYSICAL FUNCTION AMONG MEDICARE BENEFICIARIES
… relief alternatives have been sought. Recently, gabapentinoids have increased in use, specifically as a substitute for opioids in those with chronic non-cancer pain. The aim of this dissertation was to evaluate the patterns of gabapentinoid use among long-term opioid users and assess the …
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Gabapentinoids for treatment of neuropathic pain: a medicines usage evaluation at the Groote Schuur hospital chronic pain management clinic
Background Neuropathic pain (NP), defined as pain caused by a lesion or disease of the somatosensory system, affects 6.9 – 10 % of people worldwide. Pregabalin is currently recommended as a first line drug for NP in South Africa. Methods A cross-sectional retrospective descriptive medicines usage …
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The trends and rates of gabapentin and pregabalin
<b>Background</b>: Gabapentinoids were initially introduced for the treatment of epilepsy, then became more widely used in neurology, psychiatry and primary healthcare for the treatment of neuropathic pain. However, gabapentinoids have frequent and debilitating side effects, including viral …
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EVALUATING ANALGESIC INTERVENTIONS FOR ACUTE SURGICAL PAIN, PREVENTION OF PERSISTING POST-SURGICAL PAIN, AND CHRONIC LOW BACK PAIN
… assessing the effectiveness and safety of gabapentinoids (gabapentin and pregabalin) in adult patients with chronic low back pain. We observed that the existing evidence is small and there is minimal improvement in pain and other outcomes with potential for adverse events. We suggest that …
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Patterns, Variation and Mental Health Impact of Opioid Prescribing after Burn Injury
… Second, we assessed the rate of prescribing of gabapentinoids, alone or with opioids, over time to determine whether they were used as substitutes for opioid therapy. We found that gabapentinoid prescriptions alone increased significantly between 2012-2018, particularly among those over 50 years …
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The Effect of a Novel Multimodal Therapeutic Protocol on Patient Reported Post-Neurosurgical Pain Scores, versus the Current Postoperative Analgesic Practice Employed at a Local South African Hospital – An Investigator Initiated Randomized Controlled Trial
… not a multimodal analgesic regime, consisting of gabapentinoids and non-steroidal inflammatory drugs (NSAIDs) provides superior pain relief in patients undergoing elective craniotomy compared to the standard of care analgesia utilized at a local South African hospital. Methods: Twenty-seven …
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Eficacia de los gabapentinoides para disminuir la intensidad del dolor en la neuropatía dolorosa de los pacientes adultos que conviven con VIH. Revisión sistemática de literatura
Introducción: En individuos que conviven con VIH el reporte del dolor neuropático ha aumentado en los últimos años, por lo que la neuropatía por VIH representa un problema importante en la salud mundial. Los gabapentinoides, son medicamentos ampliamente utilizados en el tratamiento del dolor …