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Showing 1 to 20 of 102 for “"fungal pathogens"”.
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Molecular Analysis of Phenotypic Diversity in Human Fungal Pathogens
Fungal pathogens are a leading cause of human mortality, in part due to their ability to thwart therapeutic regimens by rapidly evolving resistance to antifungal drugs, and their ability to readily adapt to the hostile conditions experienced in a mammalian host. Candida species can colonize various …
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Hops Production in Virginia: Nutrition, Fungal Pathogens, and Cultivar Trials
In the United States, hops (Humulus lupulus L.) are grown mainly in the Pacific Northwest (PNW). For this reason, most cultural information is based on the growing conditions of the PNW. Growing conditions in Virginia differ drastically and present unique disease and production challenges. Three …
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Responses to Antifungal and Alkaline pH Stress in Human Fungal Pathogens
<p>The fungal pathogens encounter ever-changing conditions during their pathogenic life cycles, including shifts from the environment to the human host. Fungi have evolved many pathways that allow them to overcome and even thrive in the presence of the stresses presented by different …
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Analysis of the effect of atorvastatin on the virulence of Fungal Pathogens
Fungal pathogens of humans cause harmful infections and can cause diverse diseases in humans which range from superficial skin infections to life-threatening diseases. The opportunistic pathogen Candida albicans causes a wide range of diseases primarily in immunocompromised individuals. Aspergillus …
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Identification and characterization of genes in antagonism against soybean fungal pathogens by lysobacter enzymogenes
… is a potential biocontrol agent for various fungal, oomycete, bacterial, and nematode plant diseases. Understanding the molecular mechanism of LeC3 antagonism against multiple pathogens could greatly improve its biocontrol efficacy. In this study, a library containing 948 transposon-insertion …
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Modelling atmospheric dispersal of fungal pathogens on continental scales to safeguard global wheat production
… wheat fields, vast amounts of pathogenic fungal spores are produced that can be carried away by wind. For targeted disease surveillance and control it is important to estimate when, where and how many fungal spores are dispersed from infected to susceptible wheat fields. In this study, …
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Identifying and characterizing fungal pathogens causing seedling diseases on soybean through a multi-state survey
… (L.) Merr. They are caused by a variety of plant pathogens including fungi, bacteria, and oomycetes. The goal of this research was to identify fungal pathogens causing seedling diseases of soybean through a multi-state effort. Two different approaches were used for genus and species determination, …
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Brachypodium distachyon as a genetic model pathosystem to study resistance against fungal pathogens of small grain cereals
… Bd is also compatible with other important pathogens of small-grain cereals causing ramularia, eyespot and take-all diseases. In Chapter 4, a preliminary study of Bd T-DNA mutant lines altered in phytohormone biosynthesis or response investigates alteration of Fusarium resistance. Mutation …
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Fungal Pathogens Associated With Seasonal Dormancy of Zoysia Japonica: The Behavior and Interaction of Gaeumannomyces Incrustans and Rhizoctonia Solani, Coinhabitants
Zoysia japonica is a warm-season turfgrass planted throughout the transition zone of the United States that enters a period of seasonal dormancy as temperatures decline. Growth of the plant is reduced as it enters dormancy (in the fall) and exits dormancy (in the spring). Few studies have examined …
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Functional Study of Lipoxygenase-mediated Resistance to Fungal Pathogens in Maize for Milk-chain Safety and in Grapevine for Sustainable Viticulture
Fungal pathogens present a big concern in grapevine and maize production worldwide. Powdery mildew, a disease caused by an obligate biotroph, Erysiphe necator (En) is the most important fungal disease affecting grapevines, whereas. mycotoxin contamination of maize by Aspergillus flavus (Af) and …
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Evaluation of southern African maize germplasm for phytoalexin accumulation following inoculation by Fusarium verticillioides
… worldwide) that is severely affected by many fungal pathogens. The pathogen Fusarium verticillioides causes Fusarium ear rot in maize, a disease that greatly reduces quantity and quality of annual maize yields. The pathogen produces mycotoxins called fumonisins, which have been linked to …
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Exploring the potential of Antifungal Peptides to suppress the Pathogenicity of the Botrytis cinerea and Grey Mould Disease in Grapes and Strawberries
… safety has been intensively challenged by plant fungal pathogens all around the world and Botrytis cinerea which causes “Gray Mould Rot” (‘Botrytis Bunch Rot’) in fresh horticultural crops, is one of the crucial plant fungal pathogens in global agricultural industry. Currently, their effect has …
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Repurposing non-antimicrobial drugs to treat multi-drug resistant bacterial and fungal infections
<p>Bacterial and fungal resistance to conventional antimicrobials is a burgeoning global health epidemic that necessitates urgent action. Even more alarming, the development of new antimicrobials to treat these multidrug-resistant pathogens has not kept pace with the rapid emergence of resistance …
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Deciphering the mechanism of foxa2 inactivation by respiratory pathogens in chronically diseased lungs
… especially vulnerable to infection by microbial pathogens. Pseudomonas aeruginosa is an important bacterial pathogen in chronically diseased airways, especially dominant in CF and advanced stages of COPD. Pyocyanin is a redox-active virulence factors secreted copiously in CF and COPD airways by …
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Characterisation of phytoalexin accumulation in maize inoculated with Cercospora zeina, the causal organism of grey leaf spot disease
Grey Leaf Spot (GLS) is a fungal disease of Zea mays (maize) that is caused by Cercospora zeina. It thrives in sub-tropical climates and causes devastating crop losses of up to 60% in southern Africa where maize is grown as a staple food source. Phytoalexins are low molecular weight anti-microbial …
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Macrophage – cryptococcus interactions during cryptococcosis
The human fungal pathogens Cryptococcus neoformans and C. gattii cause life-threatening infections of the central nervous system. One of the major characteristics of cryptococcal disease is the ability of the pathogen to parasitise upon phagocytic effector cells. Cryptococcus can survive and …
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Effect of Physical and Chemical Cues on Candida albicans Morphological Expression and Biofilm Formation
… and biofilm formation, but their effects on fungal pathogens are less explored. This thesis systematically explores the effect of surface topography in the form of nano and microscale polymeric fibers (~0.4-1.2 µm in diameter) on biofilm formation and virulence of a common HCAI-causing fungal …
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The Role of the Glyoxylate Cycle in the Pathogenesis of Mycobacterium tuberculosis
… substrates and metabolic pathways utilized by pathogens during infection are largely unknown and represent an under-exploited area of investigation. Uniquely, evolution of the genus Mycobacterium has involved extensive duplication of fatty acid metabolism genes, including two homologs encoding …
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Antileishmania Compounds From An Unidentified Endophytic Fungus And Biotransformation Of 5,7,2`,4`,5`-Pentahydroxyflavonol
… This compound possessed significant antifungal activity against the fungal pathogens Candida glabrata and Candida krusei at IC50 4.44 and 9.56 ?g/mL, respectively. Biotransformation of 5,7,2',4',5'- pentahydroxyflavonol compound was done in an attempt to improve its biological activity.
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