Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 81 for “"fungal infections"”.
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Exploring novel predisposing factors for fungal infections
Contains fulltext : 236668.pdf (Publisher’s version ) (Open Access)
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Invasive filamentous fungal infections. Epidemiology and Host responses.
Contains fulltext : 58841.pdf (Publisher’s version ) (Open Access)
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Management of fungal infections: diagnosis and human genetic susceptibility
Invasive fungal infections represent nowadays a major public health problem with associated high mortality rates. The lack of adequate diagnostic methods, together with the fact that many emerging fungal species are resistant to the currently available antifungal agents, contributes to the profound …
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Developing novel drug combinations for treatment of invasive fungal infections
Several Fungal species have the potential to cause a broad spectrum of diseases in humans, ranging from mild superficial to disseminated invasive infections that involve the bloodstream and vital organs. Invasive fungal infections are severe, life-threatening diseases that result in the deaths of …
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Regulators of CD8+ T-cell mediated vaccine immunity against pulmonary fungal infections
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2024-08-01
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The role of autophagy in arabidopsis thaliana during biotrophic and hemibiotrophic fungal infections
… and hemibiotrophic Colletotrichum higginsianum infections. Expression of some autophagy genes was induced in A. thaliana at 9 days post infection with E. cichoracearum and, 3 and 5 days post infection with C. higginsianum. Using a transgenic A. thaliana plant line over expressing autophagosome …
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Repurposing non-antimicrobial drugs to treat multi-drug resistant bacterial and fungal infections
<p>Bacterial and fungal resistance to conventional antimicrobials is a burgeoning global health epidemic that necessitates urgent action. Even more alarming, the development of new antimicrobials to treat these multidrug-resistant pathogens has not kept pace with the rapid emergence of resistance …
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Treatment of oral fungal infections using antimicrobial photodynamic therapy: A systematic review and meta-analysis
… for “photodynamic therapy”, “conventional antifungal medication” and “oral fungal infections”. It also provides details of quantitative and qualitative methods used to analyse the effectiveness of photodynamic therapy (PDT) and conventional antifungal medications in the treatment of oral fungal …
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Development and evaluation of amphotericin B Loaded iron oxide nanoparticles for targeted drug delivery to systemic fungal infections
… to diagnose and treat life threatening invasive fungal infections (IFIs) such as cryptococcal meningitis was designed, developed, characterized, and evaluated. To address the development processes, first, iron oxide nanoparticles (IONP) (34-40 nm) coated with bovine serum albumin (BSA), loaded …
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Nanocápsulas furtivas de óleo de copaíba contendo anfotericina B: um sistema promissor no tratamento de infecções fúngicas sistêmicas
Infections caused by Candida spp. have a worldwide incidence and are considered a major challenge for public health due to its high morbidity and mortality. Although amphotericin B is used in the treatment of fungal infections, it has relevant associated toxicity. Based on that, several strategies …
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Discovery and development of novel antifungal agents for the treatment of Candida auris infections
Fungal infections are one of the leading causes of death in humans, causing infections that range from mild superficial infections to severe, and life-threatening invasive infections that affect the bloodstream and vital organs. Invasive fungal infections have a high mortality rate, leading to …
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FUSARIUM MUSAE, A NEW POTENTIAL TRANSKINGDOM PATHOGEN.
In recent years, the number of reported fungal infections has increased significantly, prompting experts to recognize invasive fungal diseases as a major public health concern. The rising threat of fungal infections has roots across the full One Health spectrum, including climate change, population …
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An assessment of Hypoxis hemerocallidea extracts, and actives as natural antibiotic, and immune modulation phytotherapies
… is used by AIDS patients to treat opportunistic infections, such as tuberculosis. The rapid emergence of multidrug-resistant tuberculosis, and extreme drug resistant tuberculosis, in recent years, is a major threat to human health. The treatment of TB, nosocomial bacterial infections, and fungal …
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The Virome in Primary and Secondary Immunodeficiency
… have historically been attributed to overt infections caused by bacterial and fungal pathogens. For this reason, treatment methods have focused on resolving these infections, with great success in terms of reducing short-term morbidity and mortality rates. This initial success only served to …
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The innate response to fungal infection
In the healthy individual fungal infections are relatively benign, however in the rapidly increasing population of immunosuppressed patients fungal infections have become an increasing cause of morbidity and mortality. In the response to fungal pathogens, the innate immune system recognises a …
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Toward the Synthesis of CAY-1, an Antifungal Steroidal Saponin
Invasive fungal infections are prevalent and often deadly in immunocompromised patients. There continues to be a pressing need for the development of novel antifungal compounds since there are currently only 13 compounds licensed for the treatment of invasive fungal infections and …
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A synthesis enabled understanding of Amphotericin B leading to derivatives with improved therapeutic indices
Systemic fungal infections represent a significant contributor to human morbidity and mortality. To lower the impact of invasive fungal pathogens on the global population, more progress must be made in the areas of diagnostic tests and safe and effective new therapies. Although Amphotericin B (AmB) …
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Damage-Induced Spatial Heterogeneity of Photosynthesis: Mechanisms and Analysis
… (phiPSII). The depression of phiPSII caused by fungal infections and galls on hardwood tree saplings extended > 2.5 times further from the visible damage and was ∼40% larger than for chewing damage. Areas of depressed phiPSII around fungal infections on oaks growing in elevated CO2 were more …
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A Mathematical Model of the Iron Regulatory Network in Aspergilus Fumigatus
Aspergillus fumigatus is an opportunistic fungal pathogen responsible for invasive aspergillosis in immunocompromised individuals. Current detection and treatment strategies for invasive aspergillosis, as well as other invasive fungal infections, are poor. Iron has been shown to be essential for …
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Probing the role of histone acetylation in the evolution of pathogenicity in <i>Candida glabrata</i>
With the advancement of modern medicine, invasive fungal infections are a growing cause of global mortality.<i> Candida glabrata</i> accounts for 25% of fungal infections in UK hospitals, second only to<i> C. albicans</i>. This number is expected to rise given current treatment challenges due to …
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