Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 326 for “"functionalised"”.
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Functionalised polymers
… carbonyl groups were unsuccessful in producing functionalised polymers. Reactions of vinyltoluene monomer were more successful. Although complications arose when lithiation and carboxylation of the monomer were carried out using lithium diisopropylamide because the carboxylic acid product …
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Synthesis of functionalised sulfonamides
… the resultant PFP sulfonate ester then provides functionalised sulfonamides of potential biological utility. In addition, the [3+2] cycloaddition reaction of several vinyl sulfonamides with N-methyl-nitrones is reported. Regiospecificity of the reaction is poor, nevertheless a diverse collection …
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Acoustic biosensing using functionalised microbubbles
In this work, functionalised microbubbles are investigated as a new platform for acoustic biosensing. In medical ultrasound, encapsulated microbubbles (MBs) are injected into the body to enhance contrast between blood and surrounding tissue. Microbubbles are not only good ultrasound scatterers: …
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Novel materials based on functionalised silsesquioxanes
… potential for potassium complexation. Vinyl functionalised silsesquioxanes have also been shown to complex platinum, in an exchange reaction with [Pt{(η-ViMe<sub>2</sub>Si)<sub>2</sub>O}(P<sup>t</sup>Bu<sub>3</sub>)]. <br></br><br></br>Investigations into the hydrosilylation reaction have …
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Organic-inorganic hybrid materials: new functionalised polyoxotungstates
Polyoxometalates are the polyoxoanions of the early transition metals, especially tungsten, molybdenum and vanadium. Although they were first described in the 19th century, their development was slow until modern experimental techniques enabled a greater understanding of their structures and …
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The Synthesis and properties of functionalised polymers
… to produce polymers that might subsequently be functionalised the polymerisation of 1,2-methylenedioxybenzene and 1,4-benzodioxane was investigated.
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Synthesis and Coordination Chemistry of Functionalised Phosphazanes
This thesis focuses on the chemistry of novel phosphazane species derived from the chloro-phosphazanes [ClP(μ-NR)]$_2$ and their use as ligands and building blocks for macrocyclic compounds. The introduction (Chapter 1) surveys previous literature in the area, which is pertinent to the new studies. …
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Phosphonium-functionalised gold nanoparticles for mitochondria targeted therapeutics.
… core sizes in the range of 2.5-5 nm. Phosphonium-functionalised gold nanoparticles have been characterised by a number of techniques including NMR, LDI-MS, SIMS, XPS, TGA, ICP-MS, MALDI-MS and TEM.Cytotoxicity studies illustrated that phosphonium ligands are relatively non-toxic to human prostate …
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Lanthanide Functionalised gold nanoparticles as MRI contrast agents
The aim of this Ph.D project was to synthesize and characterise nanoparticle-based MRI contrast agents. In the first instance, the DTPA (diethylenetriaminepentaacetic acid) based ligand was designed, synthesized and characterised. This ligand was utilised for stabilisation of gold nanoparticles. …
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Development of DNA detection assays using functionalised nanoparticles
… details the preparation of a number of biofunctionalised SERRS active nanoparticle conjugates and their incorporation into a DNA detection assay. The assay is based on a split-probe principle, with one of the probes becoming attached to a SERRS active particle giving rise to a SERRS signal …
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Functionalised self-assembled peptide hydrogel for cell transplantation
… administration. Here, we present novel bioactive functionalised self-assembly peptides (SAPs), demonstrating their inherent ability to form a shear-thinning and protective scaffold during administration. Post-injection, our biomaterials have been functionalised to provide relevant biologically …
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Functionalised self-assembled peptide hydrogel for cell transplantation
… administration. Here, we present novel bioactive functionalised self-assembly peptides (SAPs), demonstrating their inherent ability to form a shear-thinning and protective scaffold during administration. Post-injection, our biomaterials have been functionalised to provide relevant biologically …
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Functionalised metal nanoparticles as novel reagents for biomedical analysis.
… In chapter 1, topics concerning the synthesis of functionalised gold nanoparticles, their biorecognition properties, the application of these nanoparticles in the biomedical field and gold nanoparticles stabilised with phosphorus-containing ligands, are outlined in a literature review.Instrument …
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Synthesis and characterisation of novel α-functionalised phosphoryl derivatives
… of macrocyclic systems that are targeted: (i) C-functionalised α-aminophosphonic acids; and (ii) N-functionalised α-aminophosphonic acids. A novel N-functionalised macrocycle ring that includes four pendant methylenephosphonates with embedded pyridine has been successfully prepared. The strategy …
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The Fabrication of Thermoelectric Materials Using Functionalised Silicon Nanoparticles
… abundance and low toxicity. Phenylacetylene functionalised SiNPs have been synthesised using a bottom up approach. A cold pressed pellet of this material displays an electrical conductivity of 18.1 S m-1, in addition to a high Seebeck coefficient and a low thermal conductivity. These …
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Synthesis and anticancer evaluation of novel, functionalised bisindolylmaleimides and indolocarbazoles
Bisindolylmaleimides (BIMs) and indolocarbazoles (ICZs) have been reported for their potent anticancer activity. These molecules elicit their antiproliferative effects through one of the molecular mechanisms; protein kinase inhibition or interference of topoisomerase I activity. This project …
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Multi-Level Coarse-Grained Modelling on DNA Functionalised Building Blocks
… nano-sized scaffolds as building blocks. These functionalised DNA building blocks enable the formation of varied DNA functionalised systems, such as DNA liquid crystals, DNA hydrogels or DNA functionalised micelles, amongst other DNA-based materials. The properties of these large-scale DNA-based …
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The synthesis and reactivity of functionalised alkyl transition metal complexes
The complexes [CpFe(CO)₂CH₂X] and [CpW(CO)₃CH₂X] (Cp = n⁵-C₅H₅; X=Cl, Br, I) have been prepared and their reactivity with a series of tertiary phosphines, amines, SMe₂ and AsPh₃ in THF, CH₃CN and MeOH has been investigated. Two types of cationic products, namely the ylide complexes [CpM(CO)nCH₂L]+ …
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The generation and reactivity of functionalised organozinc carbenoids for cyclopropane synthesis
… describes the generation and reactivity of functionalised organozinc carbenoids for cyclopropane synthesis with alkenes. In the introductory chapter, a brief overview of the different methods for preparation of heteroatom-functionalised cyclopropanes is presented, including [2+1] …
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