Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"functional proteomics"”.
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Homology-Based Functional Proteomics By Mass Spectrometry and Advanced Informatic Methods
Functional characterization of biochemically-isolated proteins is a central task in the biochemical and genetic description of the biology of cells and tissues. Protein identification by mass spectrometry consists of associating an isolated protein with a specific gene or protein sequence in …
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A study of intrinsic disorder and its role in functional proteomics
… function arises. This view attributes the functionality of many proteins to the presence of an ensemble of flexible regions popularly as `intrinsically disordered' or `unstructured'. Several proteomic studies have corroborated the existence of either wholly disordered proteins or proteins …
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Integration Of Quantitative And Functional Proteomics To Explore The Global Functional Landscape Of Post-Translational Modifications
Proteomics explores global-scale protein functions, with post-translational modifications (PTMs) expanding proteome complexity and functionality. Significant advancements in mass spectrometry (MS)-based quantitative proteomics have expanded the scope of PTM pathways. Meanwhile, functional …
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Harnessing Cancer Omics to Inform Precision Oncology
… cerebrospinal fluid (CSF) samples. We profiled functional proteomics from kidney tumor samples using reverse phase protein array (RPPA) and formulated an MTOR score that improves prognosis prediction of recurrent risk given Leibovich risk scoring. Finally, we selected high quality user queries …
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Evaluating convolutional neural networks and transformer architectures for image-based prediction of protein localization in eukaryotic cells
… them as preferred choices for advancing functional proteomics and computational drug discovery.
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SERS & efficacy assessment of anti-cancer drug-nanoparticle conjugates
… of drugs. The purpose of this study was to functionalise a nanoparticle (NP) with an anticancer drug to be intracellularly imaged without the use of a dye. The aim was to track the uptake, distribution and release kinetics of the small molecule drug from the NP conjugate within the cell at …