Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 44 for “"functional networks"”.
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Comparison of resting state functional networks in HIV infected and uninfected children at age 9 years
… the impact of HIV and ART on the development of functional networks in 9-year-old vertically HIV-infected children compared to age-matched controls of similar socioeconomic status. We present analyses for a sample of 40 HIV+ (9.2 ± 0.20 years; 16 males) children from the Children with HIV Early …
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The role of cortical morphometry of functional networks in predicting age-related cognition in older adults
… neuroscience lens of the brain as a system of functional networks. In chapter one, I employ a widely-used functional network architecture as the organizing principle of the cortex to investigate how the cortical morphometry of individual networks predicts cognition and mediates the …
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Differences in resting state functional networks in HIV infected and uninfected children at age 7 years
… and none have measured their impact on functional brain networks in young children. We use resting state functional magnetic resonance imaging (RS-fMRI) to explore differences in functional connectivity (FC) in HIV infected children stable on HAART and in HIV uninfected children. The 9 …
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A Study of Resting State FMRI Dynamic Functional Network Analysis of MTBI
… the abnormalities and disruptions in the brain functional networks using similar methods to those employed in more severe brain disorders such as Alzheimer's or Schizophrenia. Static functional network analysis using resting state brain fMRI images has shown some promising results in identifying …
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The Effects of Chronic Sleep Deprivation on Sustained Attention: A Study of Brain Dynamic Functional Connectivity
… integration between anatomically distributed and functionally connected brain regions. Functional connectivity has been widely used to characterize brain functional integration, which measures the statistical dependency between neurophysiological events of the human brain. Further, evidence from …
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Functional Brain Connectivity Estimators: Understanding and Developing New Methodologies
… for constructing a specific part of the brain functional networks (i.e., functional connectivity or the relationship between different parts of the functional networks). In addition, we will develop new methodologies for estimating functional connectivity and propose modifications for other …
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DTI-based tractographic analysis of white matter alterations in HIV infected children
… Often, there is a link between structural and functional abnormalities. Previously, we found HIV-associated changes in white matter and functional networks in a cohort of 7-year-old HIV infected (HIV+) children who intiatied early cART compared to uninfected controls. To explore possible …
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FUNCTIONAL NETWORK CONNECTIVITY IN HUMAN BRAIN AND ITS APPLICATIONS IN AUTOMATIC DIAGNOSIS OF BRAIN DISORDERS
… Emerging of neuroimaging techniques such as functional magnetic resonance imaging (fMRI) have opened a non-invasive in-vivo window into brain function. Moreover, fMRI has made it possible to study brain disorders such as schizophrenia from a different angle unknown to researchers before. …
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Neural Mechanisms For Learning In Dynamic Environments
… the second study, I investigated how whole-brain functional networks reconfigure for the adjustment of learning. Learning rates were influenced by belief surprise and belief uncertainty, and these two variables also modulated the integration between fronto-parietal and other brain networks. This …
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Stochastic Actor-Oriented Models of Functional and Structural Human Brain Networks in Aging
… (MRI), allow for the measurement of large-scale functional and structural connectivity networks in the brain. Beyond trends, the dynamics across long timescales are still poorly understood. Our research aims to address the question of these long-term dynamics by carefully adapting and applying …
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An integrative and systems biology approach to interpreting, prioritizing, and analyzing the genetics of complex disorders.
… learning. A method for generating high-fidelity functional networks is outlined, and further, it is used for the quantification of genetic distances between classes of SUDs and cardiovascular disease. Multi-omics and multi-species graphs are integrated to prioritize SUD-associated genes. …
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Epithelial Tubular Fusion, Measuring Interconnection, and the Quest for Solving the Continuity Problem
The formation of functional epithelial tubules is a central feature of many organ systems. Although it has been well-studied how epithelial cells form tubules, it is not well understood how tubules and related epithelial micro-tissues such as spheroids and organoids interconnect with each other to …
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Subject and group level changes and comparison in functional connectivity under low vs. high cognitively demanding naturalistic viewing conditions using fmri
… determine task induced activations from cerebral networks. This study involves both rest and task activation data and implements statistical methods applied on Blood Oxygenation Level Dependent (BOLD) signals. The conventional task based designs are very specific and may not reflect day to day …
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Modelling brain tumours with network neurosciences and deep learning
… quantitative MRI technology, including functional MRI and diffusion MRI, assisted in developing an emerging field called network neurosciences. The network neurosciences model the brain as a network consisting of macro-scale regional connectivity of the brain instead of the micro-scale …
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Genome sequence of the hyperinvasive Campylobacter jejuni strains
… phenotype is characterised by different functional networks rather than a single gene or gene cluster. All strains showed an overall genetic variability and the capsule, lipooligosaccharide, flagellar biosynthesis and restriction modification regions were the most diverse. The …
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Growing synfire chains with triphasic spike-time-dependent plasticity
How collections of neurons combine into functional networks capable of intricate and accurate information processing is one of the biggest and most interesting challenges in neuroscience today. To approach this challenge, it is necessary to address the problem one structure at a time. In this …
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Neurobehavioral Mechanisms Supporting the Generalization of Learned Fear in Humans
… employs a combination of psychophysiological and functional imaging methods to examine how humans recruit neurocognitive systems to determine what stimuli do (and do not) pose a threat. Results show that human fear generalization is a complex phenomenon affected by the perceptual and conceptual …
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Novel Functional Magnetic Resonance Imaging Analysis Approaches for Investigations of the Dynamics of Resting-State Functional Connectivity
… of blood-oxygenation level-dependent functional magnetic resonance imaging (BOLD fMRI) signals are highly synchronous between brain regions that serve similar functions. This provides a means to investigate functional networks of the human brain; however, most data analysis techniques …
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Functional connectivity of the speech network in relation to reading skill in school-age children
… Development (ABCD) Study to characterize functionally-defined cortical networks for speech in school-age children and investigate the relationship between speech network connectivity and reading skill development. The first study demonstrates the feasibility of using a task-based adult …
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Synthesis and Non-Covalent Interactions of Novel Phosphonium-Containing Polymers
… and smart response. In polymers, these ionic functionalities aggregate, providing improved moduli, and altering the size and structure of ionic aggregates regulates polymer melt processability. This dissertation highlights phosphonium-based chemistry for the synthesis of novel step-growth …
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