Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"fucosyltransferase"”.
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Studies on fucosylation in Trypanosoma brucei
… of fucose in T. brucei we searched for putative fucosyltransferases in this parasite. A single putative T. brucei fucosyltransferase (TbFT) was identified and recombinantly expressed in Escherichia coli. The protein was active and structural characterization of its reaction product identified it …
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Investigating the role of ALDH3B2 and FUT2 as potential risk genes to colorectal cancer through computational analysis and gene expression study of colonic cells, and utilizing colorectal cancer cell lines to explore gene-environment interactions
… with no enzymatic functionality. FUT2 encodes a fucosyltransferase that is central to the biochemical pathway responsible for the expression of the A and B antigens in non-blood bodily fluids. At least three transcript forms of FUT2 were identified in CRC cell lines. Differences in …
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Production of a functional human milk oligosaccharide, 2'-fucosyllactose, using microbial cell factories
… a donor of L-fucose, and harbor the fucosyltransferase enzyme (FucT2) which catalyzes the transfer of L-fucose onto a lactose molecule enabling 2-FL production. Second, the production conditions of 2-FL in the engineered E. coli were optimized in order to pinpoint the appropriate …
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Determination of the prevalence and diversity of viral gastroenteritis infections and secretor status in the elderly population of the Tshwane region in South Africa
… It has been observed that an individual’s fucosyltransferase 2 (FUT2) secretor status has been associated with different degrees of infection by rotaviruses and noroviruses. A total of 1 012 stool specimens from elderly patients were collected over an 18-month surveillance period, of which …
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Metabolic phenotypes of infants with normal birth weight, small-for-gestational-age, or after maternal gestational diabetes mellitus
Numerous studies have associated both under- and overnutrition during early life with long-term metabolic outcomes. Those conditions are typically represented by two groups of infants in animal and human studies: infants born small-for-gestational-age (SGA; reflecting intrauterine undernutrition) …