Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 54 for “"freely-moving"”.
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Olfactory Processing in the Piriform Cortex of Awake, Freely Moving Mice
… an immense volume of background PC activity in freely moving animals, odor responses can be isolated from recordings and contain sufficient information to decode odor identity within a session. Across days, however, the tuning of individual cells was often inconsistent, leading to decreases in …
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Cortical Representation of Learning Social Interactions In Freely Moving Non-Human Primates
… and neural recordings to study how pairs of freely moving, interacting macaques use visually-guided signals to learn social cooperation for food reward. By recording from visual (V4) and prefrontal (dorsolateral prefrontal cortex; dlPFC) brain regions simultaneously, I examined how visual …
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Measuring prefrontal cortex response to virtual reality exposure therapy in freely moving participants
Virtual Reality Exposure Therapy has demonstrated efficacy in the treatment of phobias; yet little is known about its underlying neural mechanisms. Neuroimaging studies have demonstrated that both traditional exposure therapy and virtual reality exposure therapy normalise brain activity within a …
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Development of a head-mount fiber scanning system for imaging in vivo
… and its miniaturization for in vivo imaging in freely moving animals. The construction of a laser with enhanced repetition rate and the design of a novel non-resonant fiber scanning technique is emphasized. The increased repetition rate of the femtosecond laser source should decrease undesirable …
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Ingestible Electronics for High Quality Gastric Neural Recordings
… device for long term gastric recordings in freely moving patients known as Multimodal Electrophysiology via Ingestible Gastric Untethered Tracking (MiGUT). The custom device and electrodes are designed to conform to the stomach wall, wirelessly transmit high quality signals, all while …
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Total Surface Area in Indoor Environments
… ± standard error), and the ratio of volume of freely moving air to volume of the entire space was 0.89 ± 0.05. Ignoring contents, the surface-area-to-volume ratio was 1.9 ± 0.3 m-1; accounting for contents, the ratio was 3.7 ± 1.2 m-1. Ratios were not significantly different between room types …
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Electromechanical design of a body weight support system for a therapeutic robot for rodent studies
… a system to support the partial body weight of a freely-moving rodent. This paper discusses the design requirements, fabrication, modeling, calibration and preliminary analysis of a highly back-drivable bodyweight support system prototype. In addition, a closed loop feedback control system was …
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Wireless Neural Recording and Stimulation SoCs for Monitoring and Treatment of Intractable Epilepsy
… power overhead. In vivo measurement results from freely moving rodents demonstrate its utility in preoperative monitoring epileptic seizures. Treatment of intractable epilepsy by responsive neurostimulation requires seizure detection capabilities. Next, a low-power VLSI processor architecture for …
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Neurotransmitter and Neuromodulator Analysis Using Capillary Electrophoresis With Laser -Induced Fluorescence Detection
… from specific regions of the brain of freely moving rats appears dependent on stimulation parameters, causing differential regulation of the circadian systems.
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High bandwidth neural interfacing using visible light communication
… devices are too big and heavy to allow the freely moving behaviour of mice. Most of these use the RF based data transmission, and use larger energy storage units to supply the power required for higher data rates. The size limitations also restrict the maximum dimensions for an antenna that …
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Brain-wide representations of behavior spanning multiple timescales and states in C. elegans
… activity and the diverse motor programs of freely-moving C. elegans and built probabilistic models that explain how each neuron encodes quantitative features of the animal’s behavior. By determining the identities of the recorded neurons, we created, for the first time, an atlas of how the …
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Pitx3Null Mutant (Striatal Dopamine-Deficient) Mice Have Exaggerated Spiny Projection Neuron Responses to l-DOPA and D1 Agonism and Lack Baseline Striatonigral Spiking
… specific subsets of these neurons to spike in freely-moving wild type and parkinsonian animals causes or inhibits motor activity as predicted. However, pharmacological effects of DA deficiency, let alone those of DA replacement, on SPN spiking activity in freely-moving animals are poorly …
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Real-time tracking of olfactory information, and correlating behavior with odor plume-encounters in an olfactory-guided navigation task: On why my ethanol plumes brought all the mice to the yard
… adaptations with odor-plume contacts in freely moving mice engaged in an odor-guided navigation task.
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Characterization and connectorization of optoelectronic neural probes
… enough to chronically function in the brain of freely moving mice. Furthermore, these flexible devices enabled direct optical stimulation in the spinal cord, which for the first time allowed for direct spinal optical control of lower limb muscles. In addition to optical characterization, we have …
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Noninvasive Neuromodulation via Ultrasonic Activation of Endogenous and Exogenous Ion Channels
… striatum repeatedly evoked locomotor behavior in freely moving mice. Ultrasound sonication was confirmed to be safe based on inspection of neuronal integrity, inflammation, and apoptosis markers. This is one of the pioneering research developing sonogenetics in the mammalian brain and the first …
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A tailored biocompatible neural interface for long term monitoring in neural networks
… signals in different cortical laminae in awake freely moving animals.
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Optogenetic investigation of normal and pathological rhythms in the hippocampal formation
… stimulation and multi-site recording in freely moving animals. Toward this end, I have developed and fully characterized a novel magnetic rotary fiber optic connector for optogenetic experiments. Collectively my dissertation work provides important insight into the mechanisms of normal …
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Intelligent Cinematic Camera Control for Real-Time Graphics Applications
… the spectator either gets to control their own freely-moving camera or they get to see the view that a specific player sees. This thesis presents a system for the generation of cinematically-pleasing views for spectating real-time graphics applications. A custom real-time engine has been built …
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Simulating and calibrating stretchable optical fibers for studying neural dynamics
Study of the central nervous system (CNS) in freely-moving animal behavior experiments is greatly limited by the materials available for neural probing and optical recording, such as silica, which are stiff and can damage neural tissue with vigorous test subject movement. In this work, we develop a …
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