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FOSINOPRIL, A POTENTIAL SUBSTRATE FOR MRP2, COMPETES WITH SEVERAL HIGH USE PHARMACEUTICALS FOR ELIMINATION

Green, Benjamin

clemson Repository record for FOSINOPRIL, A POTENTIAL SUBSTRATE FOR MRP2, COMPETES WITH SEVERAL HIGH USE PHARMACEUTICALS FOR ELIMINATION (opens in a new tab)

Acer, a homologue of the human angiotensin-1 converting enzyme, modulates the response of sleep, glycogen storage, lifespan, fecundity and stress resistance to diet in Drosophila melanogaster

Glover, Zoe, Broughton, Susan, Shirras, AlanLancaster University2017

… the regulation of sleep, and the ACE inhibitor, Fosinopril, fed to flies disrupts night time sleep in the same way. This suggests a role for ACER in a circadian phenotypes in Drosophila and therefore a potential circadian role for ACE in humans (Carhan, et al., 2010). The present study has found …

lancaster Repository record for Acer, a homologue of the human angiotensin-1 converting enzyme, modulates the response of sleep, glycogen storage, lifespan, fecundity and stress resistance to diet in Drosophila melanogaster (opens in a new tab)