Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"fork dynamics"”.
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Uncovering Phosphorylation Circuitries that Control DNA Replication Fork Dynamics
… processes that enables DNA replication at the fork post replication stress. My work highlights a novel phosphorylation based signaling circuit that regulates DNA replication dynamics during replication stress recovery. This sheds light on the identity and function of the previously obscure …
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A Proteomic and Genomic Investigation Into Replication Fork Dynamics in Saccharomyces Cerevisiae
… here is an in-depth investigation into the dynamics of the proteins that associate with progressing replication forks in yeast. A focused proteomics approach is employed to specifically identify interactions between the replication fork-coupled GINS complex and other components of the …
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The role of the histone variant H3.3 and its chaperones in the response to DNA damage
… shown to be required to maintain replication fork progression in the transformed avian cell line DT40, despite the availability during replication of canonical H3. In this thesis, I have examined the role of H3.3 and its chaperones in the response to UV induced DNA damage in a non-transformed, …