Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 27 for “"foregut"”.
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Mechanisms of Foregut Formation in Mus Musculus
In mice, the foregut forms by the invagination of the anterior endoderm at embryonic day 7.5 and later gives rise to essential organs of the gastrointestinal and respiratory system. The formation of the foregut is critical for establishing the anterior organisation of the embryo, including the …
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Multiple roles of epithelial signaling during craniofacial and foregut morphogenesis
… eating arise from the pharyngeal and anterior foregut epithelium (FGE), which contains the oral ectoderm and the foregut endoderm. Proper differentiation and signaling within and from this epithelial tissue is necessary for the development of the mandible, the esophagus, and the trachea. Many …
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Underutilization of Palliative Care in Metastatic Foregut Cancer Patients Is Associated with Socioeconomic Disparities
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
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Human Embryonic Stem Cells - Constitutive Gene Expression and Differentiation Towards Definitive Endoderm and Posterior Foregut Endoderm
… to direct differentiation of hESCs towards PDX1+ foregut endoderm. The rationale for this was that both RA and FGF signaling exhibit a patterning effect during endoderm patterning and also supports pancreas specification. By optimizing the timing and concentration of RA and FGF4, it was shown that …
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The effect of varying mixtures of soybean and cereals on the landing rates of aphid vectors and spread of soybean mosaic virus (SMV) and maize dwarf mosaic virus (MDMV)
… on the incidence and spatial spread patterns of foregut-borne non-persistently transmitted plant viruses such as soybean mosaic virus (SMV) and maize dwarf mosaic virus (MDMV), and also on the landing rates of the aphid vectors that transmit them. The uniqueness of this study is that it gives an …
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FGF signaling in specification of hESC-derived definitive endoderm
… biological principles that normally control foregut endoderm and pancreas specification, numerous multifactor protocols for directing mature foregut-derived cells from hESCs have been reported. However, to establish less complex and more robust protocols there is a need to further understand …
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The use of human pluripotent stem cells to model HNF1B-associated diabetes
… and showed up-regulation of HNF1B at the foregut stage, and during pancreas specification. Homozygous knockout of HNF1B resulted in failure of foregut and pancreatic progenitor development, while heterozygous knockout of HNF1B resulted in impairment of pancreatic progenitor and endocrine …
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Comparisons of Secondary Production, Life History, and Mouthpart Functional Morphology Between Two Populations of the Amphipod Gammarus minus
… organic matter were examined. Mouthpart and foregut morphology were compared between the two populations and between immature and mature amphipods with light and scanning electron microscopy. Measurements of structure were analyzed by linear regression. A behavioral study, comparing feeding …
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Epigenetic Regulation Controls Intrinsic and Extrinsic Drivers of Gastrointestinal Development
… decisions. I further showed that loss of the foregut and hindgut lineage-specific TFs, Sox2 and Cdx2, leads to fate shifts in chromatin accessibility patterns, linking TFs, accessibility, and lineage fate decisions in gut development. Finally, I demonstrated that Sox2 overexpression in early …
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Early liver formation in zebrafish: a molecular and morphological approach
… loss of Hdac1 results in an expansion of the foregut endoderm in the domain from which the liver and pancreas originate, suggesting a scenario whereby Hdac1 may directly or indirectly restrict foregut fates while promoting hepatic and exocrine pancreatic specification and differentiation. …
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The Termite Digestome: Understanding the Digestive Physiology Involved in Lignocellulosic Biomass Degradation
… in vitro, 2) the host fraction of the gut (i.e., foregut and midgut) is the likely site of glucose absorption, 3) the termite and its symbionts contribute specific enzymes to the digestive process, 4) diet impacts biochemical and molecular aspects of termite digestive physiology, 5) the genetic …
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The metabolic sequelae of oesophago-gastric resection
… as a result of enhanced nutrient transit after foregut surgery likely underlie the early and late post-prandial symptoms seen in this group, and therapies specifically targeting the gut hormone axis, and GLP-1 in particular, could be the first targeted treatments for post-gastrectomy syndromes.
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The evolution and function of pharyngeal arch signalling centres in jawed vertebrates
… columns of tissue that form when pouches of foregut endoderm contact surface ectoderm on either side of the embryonic vertebrate head. In fishes, endodermal pouches fuse with surface ectoderm to form gill slits. Once delineated, pharyngeal arches undergo morphogenesis and differentiation, …
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Genetic and Neural Circuit Analyses of Sickness and Foraging Behaviors in C. elegans
… that are part of the nervous system in the foregut (pharynx). Collectively, these three thesis projects expand our mechanistic understanding of the neuromodulatory and circuit control of long-lasting behavioral states.
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Characterization of the molecular and biological determinants of viral dissemination from the mosquito midgut: Yellow feber virus in Aedes aegypti
… or infect and amplify in the intussuscepted foregut, cardia, and thoracic ganglia and return to the hemocoel to infect the salivary glands. Successful completion of these events is dependent on efficient receptor binding, replication, and virus packaging, maturation and release from infected …
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Age, growth, reproductive biology and diet of Spondyliosoma emarginatum (Cuvier 1830) in the West Coast National Park, South Africa
… change was estimted as 250 mm (FL). Analysis of foregut contents showed steentjies to be opportunitistic ominivores, changing from plant to animal food as they age. The average percent error and coefficient of variation values for whole otoliths were 4.59% and 6.00% respectively, and 10.89% and …
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Modelling human liver bud development in vitro
… forms a heterogenous differentiation culture of foregut derivatives which regionalise to form pancreatic, hepatic and biliary progenitors combined with cardiac and endothelial cells. After 3D seeding, these populations self-organise into complex budding structures which recapitulates the …
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Modelos de cirugía bariátrica en rata Wistar normopesa y no diabética. Cambios histológicos a nivel pancreático y en la homeostasis de la glucosa
… las teorías ya conocidas del intestino proximal (foregut) y distal (hindgut). El yeyuno, como porción intermedia, se muestra necesario y fundamental para el buen funcionamiento del islote pancreático y la consecuente regulación del metabolismo hidrocarbonado. Es la que denominamos con la teoría …
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Nutritional Ecology of the Carpenter Ant Camponotus pennsylvanicus (De Geer): Macronutrient Preference and Particle Consumption
… proventriculus contains such particles in the foregut, where they are eventually filtered from the ingluvium. Microspheres 1 μm or less were difficult to observe in the infrabuccal pocket, suggesting that they are not as effectively sequestered as larger particles. Microspheres smaller than 1 …
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Novel Non-Repulsive Outcomes From Ephrin-B Reverse Signaling
… the urethra, tracheoesophageal septation of the foregut, closure of the palatal shelves, and closure of the embryonic eyelid, defining roles for ephrin-B2 reverse signaling in each of these developmental events. Further, I show that mice with germline mutations either deleting EphB2 or similarly …
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