Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 167 for “"forebrain"”.
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Forebrain Noradrenergic Alterations and Anxiety After Myocardial Infarction
… alterations in noradrenergic transmission in the forebrain contribute to the development of anxiety disorders and arrhythmia susceptibility after MI. Using a rat coronary artery ligation model of MI, we first assessed MI-induced changes in cytochrome oxidase activity, an index of metabolic …
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Space and Value in the Primate Amygdala and Basal Forebrain
… with anatomically linked brain areas. The basal forebrain is a candidate brain area for interacting with the amygdala in influencing emotionally-guided attention given its anatomical connectivity and influence over attentional processes. Here, we analyzed data from amygdala and basal forebrain …
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THE ROLE OF DMRT GENES DURING NEUROGENESIS IN THE ZEBRAFISH FOREBRAIN
… to analyse the roles of dmrt3 and dmrt5 during forebrain development in zebrafish. Here I show that dmrt5 is a critical regulator of neuronal differentiation in the fore- and midbrain and of particular importance for the development of the telencephalon, olfactory system and the neuro-endocrine …
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Forebrain Acetylcholine in Action: Dynamic Activities and Modulation on Target Areas
<p>Forebrain cholinergic projection systems innervate the entire cortex and hippocampus. These cholinergic systems are involved in a wide range of cognitive and behavioral functions, including learning and memory, attention, and sleep-waking modulation. However, the <italic>in vivo</italic> …
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The Role of the Infralimbic-Basal Forebrain Pathway in Fear Extinction
… how IL modulates extinction is the basal forebrain (BF).</p> <p>The BF both provides and receives input from IL and BLA and has been implicated in attention and learning, including in protocols encompassing inhibition of fear responses such as fear discrimination. The role of BF-BLA …
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Dynamic Modulation of an Immediate -Early Gene in the Songbird Forebrain
… induces the IEG zenk in regions of the auditory forebrain (caudomedial neostriatum (NCM) and caudomedial hyperstriatum ventrale (CMHV)). Three hours of playback leads to the stimulus-specific habituation of this gene response. Here I show that a brief stimulus (1.5 minutes of song) was sufficient …
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Examination of neocortical plasticity during forebrain-dependent trace-associative learning tasks
… the US. Acquisition for trace conditioning is forebrain-dependent because it requires an intact neocortex and hippocampus (Solomon et al., 1986; Moyer et al., 1990; Kim et al., 1995; Weiss et al., 1999a; Takehara et al., 2002; Galvez et al., 2007). Using the trace-eyeblink conditioning paradigm …
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Functional relationship between forebrain cholinergic projections and somatostatin neurons in the rat
The two neuron types that initially degenerate with Alzheimer's Disease are the cholinergic projections from the septum to the hippocampus and from the substantia innominata to the cortex, and the somatostatinergic neurons in the hippocampus and cortex. The functional relationship between these two …
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Parkinson's disease and the influence of the forebrain dopaminergic system on dreaming
… proposed by Solms (2000) to the effect that a forebrain dopaminergic mechanism is the final common path to dreaming. It was hypothesised that sufferers of Parkinson's disease (PO) would have decreased intensity and frequency of dreams - that is that PO disease may lead to cessation or reduced …
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The Effects of Forebrain Ablations on Some Behaviors in <i>Xenopus Laevis</i>
… response strength) is the major function of the forebrain in <em>Xenopus laevis</em>. The telencephalon, however, does not play a major role in relatively simple behaviors.</p>
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The role of the kappa opioid receptor system in forebrain dependent associative learning
… for this paradigm has been demonstrated to be forebrain dependent as removal of either the hippocampus or the neocortex can either hinder, or entirely block acquisition of the association (Solomon et al., 1986, Moyer et al., 1990, Kim et al., 1995, Weiss et al., 1999, Takehara et al., 2002, …
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The role of basal ganglia-forebrain circuitry in the vocal learning of songbirds
… In songbirds, as in mammals, basal ganglia-forebrain circuits are necessary for the learning and production of complex motor behaviors; however, the precise role of this circuitry remains unknown. This thesis is an investigation into how the anterior forebrain pathway (AFP), an avian basal …
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Regulation of Circadian Rhythms by Sleep -Wake Centers in the Brainstem and Basal Forebrain
… basalis magnocellularis (NBM) in the basal forebrain, as well as the laterodorsal tegmental and pedunculopontine tegmental nuclei in the brainstem are known to play a role in regulating the sleep-wake cycle, and contain projections to the SCN. In this set of studies, C57BL/6J mice were …
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Ancient origins of the chordate forebrain: Conserved patterning of the anterior neuroectoderm in amphioxus
… most aGRN genes are expressed in the vertebrate forebrain. In this PhD thesis I trace the evolution of the aGRN across deuterostomes using the cephalochordate amphioxus as the main model organism. I first show that during amphioxus development aGRN genes are expressed in a similar pattern to the …
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Habituation of Molecular Responses to Song Stimulation in the Auditory Forebrain of Adult Zebra Finches
This dissertation reveals the complexity of molecular habituation, and serves as a starting point for further functional genomic studies.
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Cannabinoid Modulation of Reinforcement Maintained by Stimulation of the Medial Forebrain Bundle in C57Bl/6J Mice
… FAAH/MAGL inhibitor SA-57 in ICSS of the medial forebrain bundle in C57BL/6 mice. Additionally, we assessed the psychomotor stimulant cocaine as a positive control to facilitate ICSS. These studies were complimented with spontaneous locomotor activity and food-maintained operant experiments to …
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The role of the catecholaminergic projections to the forebrain in the modulation of autonomic responses to stress
… and noradrenaline (NA) in several regions of the forebrain. Although many of these regions project to brainstem nuclei involved in the control of autonomic output, the functions of the catecholamines in the modulation of responses to stressful stimuli mediated by the ANS are not known. To resolve …
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Effects of Environmental Temperature on Sleep and Waking in Normal Rats and Rats With Basal Forebrain Damage
Damage to the basal forebrain (preoptic area and surrounding structures) causes hyposomnia and impairs body temperature regulation. Normal sleep is sensitive to thermal stress--animals spend the most time asleep at thermoneutral temperatures, and amounts of sleep decline in the heat and in the …
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The Ups and Downs of MAP Kinase ERK: Modulation of Molecular Responses to Song in the Zebra Finch Auditory Forebrain
… demonstrate that ERK activity in the auditory forebrain reflects information about the familiarity and significance of a specific birdsong stimulus. Moreover, ERK activation appears to be necessary, but perhaps not sufficient, for triggering of an IEG response to song presentation. Thus ERK has …
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