Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"food antigens"”.
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CD4+ T cell response against food antigens in intestinal disease
… of the immune system is to distinguish harmless antigens, such as those found in food, from dangerous antigens. This process is known as oral tolerance and works very efficiently in healthy individuals, but it can also be disrupted, leading to food intolerances, allergies, celiac disease, or …
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DECIPHERING THE ORAL MICROBIOTA IN FOOD ALLERGY: INSIGHTS INTO THE CANDIDATE PHYLA RADIATION AND NOVEL METHODOLOGICAL APPROACHES
Food allergies are abnormal immune reactions to otherwise harmless food antigens, influenced by multiple factors, including the oral microbiota. During my PhD, I contributed to studies investigating the oral microbiota in food-allergic children, with a particular focus on the Candidate Phyla …
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Investigating the movement of intestinal intraepithelial lymphocytes using an organoid co-culture system
… absorption. It is continuously exposed to food antigens, and also several bacteria and microorganisms. Intestinal intraepithelial lymphocytes (IELs) are T cells that are interspersed between epithelial cells, above the basement membrane. This makes them one of the first immune cells to …
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IMPROVEMENT OF METAGENOMIC TECHNIQUES TO BETTER UNDERSTAND THE ROLE OF CANDIDATE PHYLA RADIATION IN FOOD ALLERGIES
Food allergies are local or systemic reactions that occur after the ingestion of normally innocuous food antigens (allergens) and can be triggered by various factors. The oral microbiota plays a critical role in the development of immune tolerance and is one of the factors involved. During my PhD I …
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IDENTIFICATION AND CHARACTERIZATION OF THE 'GUT VASCULAR BARRIER'
… is important to induce either tolerance against food antigens and intestinal flora or inflammatory responses against dangerous microorganisms. It has been demonstrated that tolerance against commensal bacteria is strictly compartmentalized, in the sense that the systemic immune system is …
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The Role of TCR Specificity in the Regulation of the Immune Response to Self and Commensal Antigens
… of the Immune Response to Self and Commensal Antigens by Stephanie K. Lathrop Doctor of Philosophy in Biology and Biomedical Sciences: Immunology) Washington University in St. Louis, 2010 Dr. Chyi-Song Hsieh, Chairperson The immune system must be able to fight potentially pathogenic microbial …
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Intestinal CD4+T Cell Responses to Food
<p>During routine digestion and absorption of food, massive quantities of diet-derived polypeptides pass through the intestine. The intestinal immune system must maintain tolerance to these dietary antigens while still protecting against pathogens and noxious agents. Oral tolerance, a robust …
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Impact of early nutrition on the development of lung immunity in the piglet
… is exposed to a variety of new environmental and food antigens. Deficiencies of the immune system, both innate and adaptive immunity contribute to impaired host defense (Marodi and Notarangelo 2007) which can lead to increased susceptibility to infection. Exposure to dietary antigens influences …
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Investigation of T cell signalling events regulating immunity and tolerance in vivo
… to discriminate between pathogenic and self or food antigens is essential not only for the generation of a productive immune response against invasive pathogens, but also for a state of antigen-specific tolerance to be elicited against harmless antigens. A breakdown in such tolerance can result …