Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"follicular dendritic cells"”.
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Age-dependent changes in the mouse lymph node and implications for immune responses
… lymphatic vessels either freely or carried by dendritic cells. I hypothesised that antigen access to the lymph node is impaired in ageing. To test this, I injected two sizes of nanoparticles, 20nm and 1000nm, enter the lymph node by free drainage in the lymph and carried in by immune cells, …
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The exploitation of neuronal survival factors in Burkitt’s lymphoma and germinal centre B cells
… expression of neurotrophin components in immune cells, the present study investigates neurotrophin component expression within Burkitt’s Lymphoma B cells. Different latency stages within Burkitt’s Lymphoma B cells are observed due to the expression of resident EBV latency genes. These B cells are …
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Compartmentalization of HIV-1 in the Secondary Lymphoid Tissues
Follicular dendritic cells (FDCs) reside in the lymphoid follicles of the secondary lymphoid tissues (sLTs). Following the infection of an individual with human immunodeficiency virus type 1 (HIV-1), viral particles are trapped in massive quantities on the surfaces of FDCs. HIV-1 viral compartments …
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Signals for B cell activation in antibody response
… B cell receptor by interaction with antigen on follicular dendritic cells (FDCs) may be an important selection process to select high affinity B cell clone. As antigen on FDC is present in the form of antigen-antibody immune complex, GC B cells are expected to have to compete with antibody to …
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Antibody-Mediated Modulation of Polyclonal Immune Responses
… line of defense, and consists mainly of myeloid cells that are quickly activated within hours to days to engage in a non-specific manner. This broad response is followed by the adaptive immune response, which progresses more slowly but is capable of generating pathogen-specific immunity. …
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Stromal components and the control of lymphocyte trafficking in human lymph nodes
… LNs requires better knowledge of the stromal cells and structural components of the LN with which immune cells interact. We sought to characterise the stromal components of human LNs and examine the factors controlling lymphocyte migration within human LNs. This study for the first time …
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Engineering kinetics of immunotherapies and vaccines
… due to their ability to activate innate immune cells. Nevertheless, safe and effective systemic administration of these compounds in the clinic is an unsolved challenge due to dose-limiting toxicities, poor bioavailability, and severe immune-related adverse events upon intravenous …