Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"follicle growth"”.
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Mechanism of Bisphenol A toxicity in adult mouse ovarian antral follicles
… endocrine responsive processes such as ovarian follicle growth and steroidogenesis. Follicles are the functional units of the ovary, responsible for ovulating an oocyte and producing sex steroid hormones during steroidogenesis. Follicles grow and develop from primordial, primary, pre-antral, and …
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Equol inhibits growth, induces atresia, and inhibits steroidogenesis of mouse antral follicles
… which could in turn influence ovarian follicle growth. However, no studies have examined the direct effects of equol on intact antral follicles, which are responsible for sex steroid synthesis and further development into ovulatory follicles. The present study tested the hypothesis that …
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Gene expression underlying ferret hair growth initiation induced by melatonin and modified by steroids
… gene expression associated with the hair growth cycle. The effects of melatonin and steroids on hair follicle growth initiation in flank skin samples were monitored by histology and immunocytochemistry. Melatonin implantation initiated hair growth within 10 days. Exogenous steroids …
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The effects of adult exposure to genistein on female reproductive outcomes
… is because the ovary’s main functional unit, the follicle, is responsible for the production of sex steroid hormones and consists of the oocyte necessary for fertilization. In the adult ovary, the follicle is present in all stages ranging from the immature primordial follicle to the most mature …
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Mechanism of methoxychlor toxicity in mouse ovarian antral follicles
… fertility by increasing atresia of antral follicles and by decreasing numbers of healthy antral follicles in adult female mice. Further, MXC inhibits growth and induces atresia of mouse antral follicles in vitro. Little is known, however, about the mechanisms by which MXC causes slow growth …
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Prolactin signalling in murine hair growth
Although prolactin has been shown to entrain hair growth cycles in seasonally responsive mammals, no comparable role has been identified in the age-dependent pelage replacement of rodents. Prolactin binds to dimerised membrane-associated prolactin receptors (PRLR) on target organs and initiates …
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Elucidating the Function of Krüppel Homolog 1 (Kr-h1) Associated Proteins (KAPs) in Aedes aegypti Reproduction Through RNA Interference-Mediated Downregulation
… identifies DP-1 as a significant regulator of follicle growth post-eclosion (PE), highlighting its vital role in the mosquito reproductive regulatory pathway. The experimental approach included RNAi-mediated knockdown of DP-1, accompanied by evaluations using quantitative PCR (qPCR), Western …
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Potensi ekstrak daun pegagan (Centella asiatica (L.) Urban ) dosis tinggi sebagai antifertilitas pada mencit (Mus musculus) betina
… organ, for example development of ovarium’s follicle. Those active material regeneration cells of ovarium granulose which produce the inhibidin for the result, where as inhibidin will hamper secretion of gonadotropin hormone, especialy FSH. This research done in biology departement …
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The effects of an environmentally relevant phthalate mixture on female reproduction
… are born with a finite pool of primordial follicles, and the size of primordial follicle pool determines the reproductive lifespan. To form the finite pool of primordial follicles, germ cells must undergo mitosis, formation of germ cell nests, meiosis, and germ cell nest breakdown. Any …
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The aryl hydrocarbon receptor signaling pathway and adverse reproductive outcomes
… senescence by directly targeting ovarian follicles. Thus, in my dissertation work, I tested the hypothesis that various doses of bisphenol A (BPA) inhibit growth and reduce estradiol biosynthesis in isolated mouse antral follicles. I also tested the hypothesis that the toxic effects of BPA …
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Development of a novel, clinically-relevant model for investigating factors that stimulate human hair growth
… agents are currently available to stimulate hair growth; their development is hampered by inappropriate model systems. Most research involves large terminal scalp follicles rather than the clinical targets of tiny vellus or intermediate follicles. The overall aim of this thesis was to develop a …
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Investigations into the roles of potassium channels in hair growth. Studies confirming the presence of several ATP-sensitive potassium (K+ATP) channels in hair follicles and exploring their mechanism of action using molecular biological, cell culture, organ culture and proteomic approaches.
… though SUR1 and SUR2B are present in human hair follicles. To expand our understanding, the red deer hair follicle model was used initially. Deer follicles expressed the same KATP channel genes as human follicles when growing (anagen), but no channels were detected in resting follicles. This …
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Investigating the role of ephrins and their receptors in mouse folliculogenesis and ovulation
Follicle stimulating hormone (FSH) promotes granulosa cell (GC) proliferation, differentiation, and steroidogenesis. This series of events is critical for female fertility, and culminates in the formation of mature follicles responsive to the surge of luteinizing hormone (LH) that triggers …
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The role of vascular endothelial growth factor isoforms in early follicle development
… vascularization of the theca layer increases as follicles progress in size through preantral and antral stages, the principal angiogenic factor, vascular endothelial growth factor A (VEGFA), may influence follicle growth via regulation of angiogenesis. However, VEGFA may also influence follicular …
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Toxicity and detoxification of imidacloprid in mouse ovarian follicles
… to test the hypothesis that IMI causes ovarian follicle toxicity via acetylcholine pathways and the ovary itself contributes to this ovotoxicity using its metabolic machinery. In Chapter 3, I compared the effects of IMI and DNI on antral follicle physiology in vitro. Antral follicles were …
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MORPHOMETRIC AND MOLECULAR STUDIES OF THE CORRELATION BETWEEN CHRONIC MASTITIS AND INFERTILITY IN DAIRY CATTLE
… ovarian stroma with matrix fibers, follicular growth factors, characteristic micro-architecture of stromal vasculature, as well as growth and development of follicles by macroscopic and microscopic morphological as well as immuno-detection based molecular analysis of the ovaries collected at …
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The serum concentrations of anti-Mullerian hormone (AMH), thyroid-stimulating hormone (TSH), free triiodothyronine (fT3) and free thyroxine (fT4) during early pregnancy
… ovarian insufficiency. AMH also influences follicle growth, but the precise mechanism by which it does this is unknown and its role during pregnancy has not been adequately characterised. In this study the key findings regarding AMH were the differences between preovulatory and luteal phase …
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Exploring Molecular Mechanisms Controlling Skin Homeostasis and Hair Growth. MicroRNAs in Hair-cycle-Dependent Gene Regulation, Hair Growth and Associated Tissue Remodelling.
The hair follicle (HF) is a cyclic biological system that progresses through stages of growth, regression and quiescence, each being characterized by unique patterns of gene activation and silencing. MicroRNAs (miRNAs) are critically important for gene silencing and delineating their role in hair …