Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"follicle development"”.
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The role of vascular endothelial growth factor isoforms in early follicle development
… vascularization of the theca layer increases as follicles progress in size through preantral and antral stages, the principal angiogenic factor, vascular endothelial growth factor A (VEGFA), may influence follicle growth via regulation of angiogenesis. However, VEGFA may also influence follicular …
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External and internal factors influencing ovarian follicle development in weaned sows and the use of hormonal technology to improve subsequent fertility
The student, Lidia Sbaraini Arend, accepted the attached license on 2022-04-20 at 14:45.
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Investigation of regulatory functions of micrornas in skin and hair follicle development and cycling. A role of microRNA-214 in skin and hair follicle homeostasis.
… physiological processes, including skin and hair follicle (HF) development. In this study, the role for miR-214 in the skin and HF development and their postnatal physiological regeneration was investigated. miR-214 exhibits discrete expression patterns in the epidermis and HF in developing and …
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ULTRASOUND CHARACTERIZATION OF ANTRAL FOLLICLE DYNAMICS ACROSS THE ADIPOSITY SPECTRUM
… hormone pulse amplitude in addition to lower follicle stimulating hormone (FSH) and anti-Mullerian hormone (AMH) production, albeit controversial. These endocrine aberrations likely reflect alterations in antral ovarian follicle development, but this has never been systematically evaluated in …
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Specification And Function Of Early Hair Follicle Stem Cells
… in a quiescent niche associated with each hair follicle termed the "bulge" and are essential for cyclic bouts of hair growth. Bulge stem cells can also contribute to sebaceous glands and the intefollicular epidermis when it is injured. While hair follicles begin to develop during embryogenesis, …
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Dysregulation in polycystic ovary syndrome: mechanisms and therapeutic approaches
… hormone (GnRH), luteinizing hormone (LH), and follicle- stimulating hormone (FSH). Women with PCOS, experience irregular GnRH signaling that leads to an overproduction of LH and a reduction in FSH, which in turn stimulates excessive androgen production and hinders proper follicle development. …
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Expression pattern and role of Foxcl during hair follicle morphogenesis
… pattern during embryonic and neonatal skin development, this study utilised mice in which the Lac-z reporter gene was placed under the control of wild-type Foxcl promoter by homologous combination (Kume et al, 1998, Cell 93, 985-996). Lac-z encodes enzymatically active ~-galactosidase, which …
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Molecular Regulation of Hair Follicle Morphogenesis
… during embryogenesis. Morphogenesis of hair follicles is initiated when a series of reciprocal interactions between this undifferentiated ectoderm and its underlying mesenchyme leads to a localized invagination of epithelial cells. As hair follicle development proceeds, stem cells are …
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MULTISCALE TECHNOLOGIES FOR ENGINEERING AND CRYOPRESERVING OVARIAN TISSUES AND HUMAN IPSCs
… of the tightly controlled process of ovarian follicle development. Impaired fertility can arise from disorders like polycystic ovarian syndrome (PCOS) or premature ovarian insufficiency (POI), which affect the function of the ovary, an integral reproductive organ that houses the ovarian …
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The Effects of a GnRH Antagonist, Cetrorelix, on Ovarian Function in Cattle
… would induce regression of the dominant follicle and induce a new follicular wave emergence at a predictable time after treatment. In the first study (Chapter 4, two experiments), we explored the effects of cetrorelix at three stages of dominant follicle development and synchrony of …
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Investigating the role of PABPC5 in mouse physiology
… while others are limited to specific tissues and developmental time points (e.g., ePABP). The best described member, PABP1, has been found to be essential for the translation of messenger RNA to protein according to in vitro data. However, there is limited literature characterising the role of …
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Sex as a Biological Variable in Preclinical Animal Studies with an Infectious Disease Exemplar.
… as an independent risk factor for disease development. Emerging evidence has suggested that sex- and hormones play a protective role against disease susceptibility. Despite evidence suggesting the importance of sex in this disease these variables remain poorly integrated into preclinical …
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Characterization of Microrna Expression Profiles and Role of Nodal-Related Genes in Zebrafish Ovarian Follicles
… of reproduction as the processes that regulate follicle development and oocyte maturation are conserved among vertebrates. In zebrafish, early vitellogenic (stage IIIa) ovarian follicles are maturationally incompetent while mid-late vitellogenic (stage IIIb) follicles are able to undergo oocyte …
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Role of Insig-Mediated Cholesterol Homeostasis in the Development of the Palate and Hair Follicles in Mice
… cholesterol homeostasis is crucial in mammalian development. Currently, there are 8 known human malformation syndromes due to genetic defects in cholesterol biosynthesis. Patients with these syndromes present with a constellation of developmental defects, ranging from skeletal and craniofacial …
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EGFR Signaling Is Necessary for Gonadotropin-Induced Steroidogenesis and Oocyte Maturation
… of steroids and their receptors on oocyte and follicle development. Initial work focused on transcriptionindependent, or nongenomic, steroid-induced maturation of oocytes. We demonstrated for the first time that steroids trigger oocyte maturation in several different mouse models, activating G …
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Computer-Assisted Image Analysis of Human Ovarian Follicles: Imaging Physiologic Selection
… involves recruitment of a cohort of small follicles, physiological selection of a dominant follicle, and ovulation. The mechanism of selection has not been precisely determined. Identification of the timing of preovulatory selection is a key component in understanding natural and …
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Impacts of microenvironment variation during breeding and gestation on the reproduction and well-being of mature gilts
… any response variable. Reproductive measures of follicle development, expression of estrus, ovulation rate, pregnancy rate (83.2%), litter size (14.3 +/- 0.5), and fetal measures were not affected by temperature or lighting (P > 0.10). Gilts in COLD (37.6 C) had a lower (P < 0.05) rectal …
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Towards elucidating the function of the oocyte Subcortical Maternal Complex: A multi-omic analysis of an Nlrp5-null murine model
… NALP5 and, by extension, the SCMC, in oocyte developmental competence. This study focuses primarily on elucidating the role of NALP5 in the context of DNA methylation patterning in the oocyte. This was done by establishing a null mouse line for *Nlrp5*, the gene encoding NALP5. A phenotypic …
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TRANSCRIPTOME LANDSCAPE OF EARLY FOLLICULOGENESIS IN MAMMALS: UNLOCKING THE INTERPLAY MECHANISMS TO ENHANCE ART EFFICIENCY IN FERTILITY PRESERVATION
… female gamete reserve, specifically the antral follicles. In contrast, the preantral follicle population, which represents 99% of the reserve, remains unexploited. To date, no established culture system has been successfully adopted to replicate folliculogenesis in vitro, as existing approaches …
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Rescue of ovarian function: stem cells and regenerative factors
… they might contain a residual pool of quiescent follicles that could be rescued. Soluble factors secreted by stem cells could provide an adequate ovarian environment to maintain and promote follicular growth. Therefore, the present study aimed to assess the regenerative effects of different …
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