Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"fold repression"”.
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Characterization of the glpEGR operon of Escherichia coli K-12
… with results previously reported on differential repression of these operons. Under the conditions employed, the glp repressor conferred more than 90-fold repression on glpK. Interestingly, in the presence of GlpE and GlpG, the repression ratio for glpK increased to near 170-fold. In contrast, …
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RNA tools for optimization of multi-protein genetic systems
… of a ribosome-binding site to generate up to 175-fold repression when maximally expressed. By controlling sRNA expression, the targeted gene can be tunably repressed from 1.6- to 121-fold. We then built a pool where each of the six sRNAs was placed under the control of 16 promoters, yielding ~107 …
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Dynamic regulation of pathways by down-regulating competing enzymes
… transactivating system (tTA) that enables repression of Hxk1 up to 10-fold in activity upon addition of doxycycline. Downregulation of this competing Hxk1 enzyme resulted in a 50-fold increase in gluconic acid and a 3-fold improvement in isobutanol yields from glucose. Extending this …
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Dicer loss induces an oncogenic epigenetic switch in mesenchymal stem cells
… that tune gene expression. Despite the modest 2-fold repression that miRNA activity generally confers on a target, miRNAs are critical for many biological processes including development and differentiation. Due to this mild repression directly conferred by miRNA activity, miRNAs coordinate with …
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Competition and band-pass filtering in biology: modelling and experimental validation in membrane trafficking and post-transcriptional gene regulation
L'abstract è presente nell'allegato / the abstract is in the attachment