Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"focal segmental glomerulosclerosis"”.
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alpha-Actinin-4 and the podocyte: Implications for focal segmental glomerulosclerosis
Focal and segmental glomerulosclerosis (FSGS) is a common glomerular lesion and a significant cause of end-stage renal disease (ESRD). FSGS lesions result from damage to glomerular epithelial cells called podocytes, a key cell type involved in glomerular filtration. Mutations in the ACTN4 gene, …
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Electron microscopic morphometry of podocyte foot process effacement as a tool to distinguish primary from secondary focal segmental glomerulosclerosis (FSGS)
Background: Focal segmental glomerulosclerosis (FSGS) is a histological pattern of glomerular injury and one of the most common causes of end-stage renal disease in adult patients. Two major subtypes of FSGS (primary oand secondary) have been identified, with differences in clinical presentation, …
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Engineering Complex Kidney Structures for Disease Modelling, Drug Testing, and Studying Kidney Development
… heterozygous <i>PAX2</i> mutation affected by focal segmental glomerulosclerosis, we speculated that such developmental disorder might have contributed to the patient’s condition. <br></br><br></br> Overall, these findings document that our innovative and robust technology for controlled tubule …
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Clinical Presentation and Histopathological Description of the Spectrum of Renal Diseases in HIV Infected Adults Presenting With Renal Insufficiency at the University Teaching Hospital,Lusaka Zambia
… immune complex kidney disease (HIVICK) (32%) and focal segmental glomerulosclerosis (FSGS) (29%) of various histologic variants other than the collapsing type. We did not see the classic HIVAN on histopathology in our study population. All the patients presented with severe renal dysfunction with …
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Clinical Presentation and Histopathological Description of the Spectrum of Renal Diseases in HIV Infected Adults Presenting With Renal Insufficiency at the University Teaching Hospital,Lusaka Zambia
… immune complex kidney disease (HIVICK) (32%) and focal segmental glomerulosclerosis (FSGS) (29%) of various histologic variants other than the collapsing type. We did not see the classic HIVAN on histopathology in our study population. All the patients presented with severe renal dysfunction with …
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Studying glomerular disease epidemiology: tackling challenges and paving a path forward
… in the 21st century of the rapid increase in focal segmental glomerulosclerosis observed at the end of the 20th century, and a dramatic increase in diabetic glomerulosclerosis over time, to become the second most frequent biopsy-proven glomerular disease diagnosis in the modern era; c) …
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Ca²⁺ and phosphoinositides regulations in α-actinin -4 F-actin binding.
… (NSCLC), small cell lung cancer (SCLC) and focal segmental glomerulosclerosis (FSGS). The mutation site within these mutants is located on the actin binding region. Therefore, the actin binding region is presumed to be associated with the progression of human disease. The aims of this thesis …