Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"focal cerebral ischemia"”.
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Astrocyte metabolism following focal cerebral ischemia
… of either the response of astrocytes to cerebral ischemia or the extent to which these cells can recover function if blood flow is restored. The main aim of the project was to assess key metabolic properties in astrocytes during early reperfusion following unilateral occlusion of the …
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Retinale Ischämie bei der intraluminalen Fadenokklusionsmethode
… methode is an established model to induce a focal cerebral ischemia. Considering the blood supply of the retina, the induction of a retinal ischemia with the intraluminal suture methode (ILSM) is possible. In this experiment we induced a transient retinal ischemia in Sprague-Dawley-rats by …
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Zytokinexpression in der ischämischen Penumbra nach transientem Verschluß der A. cerebri media in der Ratte
… penumbra at various times after transient (3h) ischemia. We chose the intraluminal suture method to produce an occlusion of the middle cerebral artery (MCA-O) in rats. The animals were killed at 1, 3, 7 or 14 days following operation. Coronal brain sections were processed for astroglial (GFAP), …
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Pre-clinical Targets for Ischemic Brain Injury
… and 87% of strokes result from a blockage in the cerebral blood flow which results in ischemia. Injury to the myelinated axons located in white matter is observed in ischemic injuries but is generally underappreciated. Research has shown that there is extensive vesicular glutamate release during …
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Deficits in Auditory, Cognitive, and Motor Processing Following Reversible MCAO in Mice: Understanding the Human Stroke Phenotype
… and/or bodily function resulting from a cerebral vascular accident (interruption of blood flow to the brain). Acute ischemic stroke is the third leading cause of death in the United States, and the leading cause of long-term functional disability in adults. Stroke-induced deficits may …
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The Effect of Selective Hypothermia on Stroke Volume
Hypothermia is a well-established neuroprotectant. Selective hypothermia to the ischemic area may eliminate side effects while improving induction time. We studied the effect of selective hypothermia on stroke volumes in adult domestic swine. Under general anesthesia, one MCA was occluded …
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Neuronal Differentiation and Functional Recovery after Transplantation of Human Mesenchymal Stem Cell in The Ischemic Rat Model
… stem cells were transplanted via tail vein into cerebral ischemic rat model exposed to transient MCA occlusion. We examined that cytokine-inducted human mesenchymal stem cells transplanted in brain had survived and differentiated into neural cells and neurological functions were improved after …
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MAPK and pro-inflammatory mediators in the walls of brain blood vessels following cerebral ischemia
… an important role in the development of the cerebral lesions [6]. This inflammatory reaction involves activation of resident cells (mainly microglia), infiltration and accumulation of various inflammatory cells (including neutrophils, leukocytes, monocytes, macrophages), and production of …