Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"focal adhesion complex"”.
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Mechanotransduction by talin : a molecular dynamics study of force-induced recruitment of vinculin to a focal adhesion complex
… Talin, an essential structural protein in the adhesion, contains the N-terminal five-helix bundle in the rod domain with a known cryptic vinculin binding site 1 (VBS1). The perturbation of this stable structure through elevated temperature or destabilizing mutation activates vinculin binding. …
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Trimethoprim-Based Chemical Tags for High Resolution Live Cell Imaging
… TMP-tag technology to study the dynamics of the focal adhesion complex at the single-molecule level. Finally, I also tried to develop a short peptide tag for protein labeling with minimal perturbation of the function and dynamics of the target molecule. Together, these studies exemplified the …
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Integrinaktivierung und Formation des "fokalen Adhäsionskomplexes" im Hypertrophieprozess adulter Mäuseherzen
… wir als Zytoskelett-assoziierte Tyrosinkinasen, „focal adhesion kinase“(Fak) und c-Src, identifizieren, welche beide zum sogenannten Integrin-abhängigen fokalen Adhäsionskomplex gehören. Weitere Analysen zeigten Phosphorylierungen von Fak bei Tyr-397 und Tyr-925, c-Src bei Tyr-418. Dies lässt …