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Showing 1 to 1 of 1 for “"fluoromethyl ketones"”.
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Fluoromethyl ketone prodrugs: Potential new insecticides towards Anopheles gambiae
… vitro assay studies demonstrate that tri- and difluoromethyl ketones can potentially inhibit An. gambiae AChE (AgAChE). These compounds inhibit the enzyme by making a covalent adduct with the catalytic serine of AChE. Trifluoromethyl ketones however are poor inhibitors of the G119S resistant …