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Showing 1 to 3 of 3 for “"fluorinated analogs"”.

  1. I.~fluorine-18 Labeled Corticosteroids and Progestins for Receptor-Based Imaging of the Brain and of Breast Tumors. II.~Synthesis and NMR Spectrum of (carbon-13(18))-Meso-Hexestrol

    … fluorine-18 labeled ligand. We have prepared fluorinated analogs of six natural and synthetic corticosteroids as potential diagnostic imaging agents for Alzheimer's dementia. Four of these ligands have been prepared in fluorine-18 labeled form (three in high specific activity, 369-1618 …

    uiuc Repository record for I.~fluorine-18 Labeled Corticosteroids and Progestins for Receptor-Based Imaging of the Brain and of Breast Tumors. II.~Synthesis and NMR Spectrum of (carbon-13(18))-Meso-Hexestrol (opens in a new tab)

  2. Design, synthesis, and biochemical evaluation of three types of hexestrol-based probes for estrogen receptor: Fluorine-18 radiopharmaceuticals, bivalent ligands and diazirine photoaffinity reagents

    … structure, and function. We have prepared two fluorinated analogs of 2-oxohexestrol as potential diagnostic imaging agents for ER-responsive human breast tumors. These ligands were prepared in fluorine-18 labeled form with high specific activity (328-609 Ci/mmol) by fluoride ion …

    uiuc Repository record for Design, synthesis, and biochemical evaluation of three types of hexestrol-based probes for estrogen receptor: Fluorine-18 radiopharmaceuticals, bivalent ligands and diazirine photoaffinity reagents (opens in a new tab)

  3. Synthesis of fluorinated cannabinoid derivatives; Towards PET radiotracers for imaging the cannabinoid receptor

    … and humans. Our major focus was to prepare novel fluorinated analogs of tetrahydrocannabinol (THC)-type, cannabidiol (CBD)-type, cannabicyclol (CBL)-type, and cannabichromene- (CBC)-type plant cannabinoids from Cannabis sativa as PET tracer candidates. Synthetic routes were developed leading to …

    sask Repository record for Synthesis of fluorinated cannabinoid derivatives; Towards PET radiotracers for imaging the cannabinoid receptor (opens in a new tab)