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Showing 1 to 20 of 100 for “"fluorescent probes"”.
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The Effects of Highly Reflecting Materials on Nearby Fluorescent Probes
… the effects of highly reflecting materials on fluorescent molecules spaced within several thousand angstroms of that surface. The specific light environment resulting from reflection will affect the emission intensity and the lifetime of the excited state of these molecules. A layered system …
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Turn-on fluorescent probes for detecting nitric oxide in biology
… Oxide and Other Reactive Nitrogen Species Using Fluorescent Probes: This chapter presents an overview of recent progress in the field of reactive nitrogen species (RNS) sensing. Reactive nitrogen species, such as nitric oxide (NO) and its higher oxides, play important roles in cell signaling …
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Metal-based turn-on fluorescent probes for nitric oxide sensing
Chapter 1. Metal-Based Turn-On Fluorescent Probes for Sensing Nitric Oxide. Nitric oxide, a reactive free radical, regulates a variety of biological processes. The absence of tools to detect NO directly, rapidly, specifically and selectively motivated us to develop metal-based fluorescent probes to …
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Tetrahydrochrysene and cyclofenil derivatives as fluorescent probes of the estrogen receptor
… (THC) derivatives IIIb-e as the first fluorescent estrogens, designed to satisfy the criteria for a direct fluorometric assay of the estrogen receptor in cells. The preparation of unsymmetrical chrysenes IIIb-e, containing ketone, ester, amide, and nitrile groups, was achieved …
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Extending the utility of enzymes for site-specific targeting of fluorescent probes
… fluorescence reporters such as the green fluorescent protein (GFP) are useful for studying protein expression, localization, and dynamics in a variety of biological systems. GFP and its related variants, however, suffer from several drawbacks. Compared to chemical fluorophores, they are …
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Phosphine Based Fluorescent Probes for Nitroxyl Detection and Their Reactivity Toward S-Nitrosothiols
Nitrogen oxides are a unique class of molecules with profound physiology. Nitric
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Development of Endoplasmic Reticulum Targeted Probes and Red Fluorescent Probes for Detecting Zinc
… is important in various biological functions. Fluorescent sensors based on circularly permuted fluorescent proteins (cpFPs) have been previously made to detect labile, or unbound, Zn<sup>2+</sup> within the cytoplasm of cells. These sensors have proven invaluable for studying Zn<sup>2+</sup>, …
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Using Fluorescent Probes to Study the Location and Interaction of Disaccharides within Lipid Bilayers
It is well known that certain organisms, such as the tardigrade, are capable of surviving extreme conditions including dehydration, freezing and / or oxygen deficiency. The tardigrades ability to withstand such extreme conditions is associated with a decrease in its internal water content and the …
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Fluorescent probes and nanostructured materials for the detection of environmental toxins and catalysts development
La tesis trata sobre la síntesis y utilización de materiales modificados, para el reconocimiento de distintas sustancias por fluorescencia o para el desarrollo de catalizadores de reacciones orgánicas de interés. En la primera parte de la tesis se desarrollaron sensores de sustancias tóxicas como …
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Characterization and Synthesis of Cyclodextrin Inclusion Complexes and their Applications as Fluorescent Probes for Sensing Biomacromolecules
… agent was fully explored. Furthermore, two CD probes are synthesized and are shown to display differential fluorescent responses with a small series of proteins.
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Characteristics and Performance of Novel Squarylium Dyes as Fluorescent Probes for the Analysis of Proteins and Viruses by CE-LIF
… organic dye molecules to act as noncovalent fluorescent labels to aid biomolecule detection. Noncovalent binding of dyes through hydrophobic, electrostatic, and other interactions with biological molecules can result in improved sensitivity by assays using capillary electrophoresis with laser …
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Towards the development of fluorescent probes targeting aldehyde dehydrogenase (ALDH) in cancer. Expression and epigenetic modulation of ALDH1A1, ALDH2 and ALDH3A1 in selected in vitro models.
… and demonstrating their potential as molecular fluorescent probes to identify CSCs. The AAQs were shown to be subjective to acidic hydrolysis using 2M HCl at 37ºC; however compounds containing secondary or tertiary amine functionalities in their sidechain were only partly hydrolysed at 70 ºC. …
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Towards the development of fluorescent probes targeting aldehyde dehydrogenase (ALDH) in cancer. Expression and epigenetic modulation of ALDH1A1, ALDH2 and ALDH3A1 in selected in vitro models.
… and demonstrating their potential as molecular fluorescent probes to identify CSCs. The AAQs were shown to be subjective to acidic hydrolysis using 2M HCl at 37ºC; however compounds containing secondary or tertiary amine functionalities in their sidechain were only partly hydrolysed at 70 ºC. …
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Aspects of bioorganic chemistry - a). Development of caffeine-aptamer for coffee decaffeination; b). Study of 1,8-naphthalimide derivatives as fluorescent probes; c). Encapsulation of DNA by silica nanoparticles
… polarity, where the compound is virtually non-fluorescent in DMSO, large folds of fluorescence turn-on were seen in less polar solvents. Furthermore, this compound showed aggregation-induced emission characteristics. 4-Aryl-N-ethoxyethyl- and …
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Preparation of 7-(p-Substituted-Benzylamino)-4-Nitrobenzoxadiazole Derivatives and the Study of their Fluorescent Properties in Solution
… and study their fluorescent behavior in aqueous-nonaqueous solvent systems. The parent compound has been used by others as a fluorescent probe to determine the conformation changes of bovine trypsinogen and bacterial libosomes. Fluorescent probes have been used to: …
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