Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"flow focusing"”.
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Microfluidic flow-focusing device for the electrospinning of hollow polymer nanofibers
… designed and assembled for the two-dimensional focusing of immiscible fluids and integrated into a system for electrospinning. Hollow fibers were produced with diameters on the order of 100-240 nm, at steady-state flow rates around 50 pL/min. TEM images show hollow interiors with diameters …
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Fluid Mechanics for Biomedical Applications: Weakly Viscoelastic Electrospray, Flow Focusing and Collapsible Channel Models
… ii) the emergence of whipping effect on the Flow Focusing technique, and iii) fluid-structure interaction (FSI) phenomena implementing a 2D collapsible channel model. i) A systematic, theoretical comparison of a Newtonian fluid, and a non-Newtonian one modelled using an Oldroyd-B model was …
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Microfluidic emulsion characterization for the development of armored droplet arrays
… to determine the best method for using a flow-focusing device to produce monodisperse water droplets in a polymer flow with sufficient spacing to polymerize a protective shell around the droplets using continuous flow lithography. Contact angle measurements and surface tension measurements …
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Increased production of aligned cellulose nanofibrils using microfluidic mixture chambers
… fibers from cellulose nanofibrils using flow focusing in microfluidic mixture chambers is examined and tested. This process accomplishes the difficult task of aligning cellulose nanofibrils and gelling them together to create macroscale cellulose fibers, and this study seeks to test the …
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Analysis of Solute Mixing at the Pore-Scale Using Micromodels and Lattice -Boltzmann Finite Volume Modeling
… (FVM) utilizing identical pore structures and flow rates. The LB method is used to solve for interstitial pore velocities. Reactive transport is simulated by combining pore velocities from the LB model with a reactive transport FVM model. Pore scale modeling and experimental results are …
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A Management Paradigm for FPGA Design Flow Acceleration
… overview of an incremental productivity flow, focusing on the back-end FPGA design is provided in this thesis. This thesis presents a management paradigm that is used to capture the design specific information in a format that is reusable across the entire design process. A C++ based …
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Uniqueness problems in mean curvature flow
… uniqueness phenomena in mean curvature flow, focusing on two central problems: the behavior of the flow near singularities and the extension of the flow beyond singular times. These questions have significant applications in geometry, topology, and analysis. For the first problem, with …
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Microfluidic Study of Gravity-Driven Drainage and Coalescence of Aqueous Two Dimensional Foams
… <p>We developed a system using microfluidic flow-focusing devices to generate mono-disperse, vertical 2D foams and capture the drainage, coalescence and coarsening processes in high resolution. Our analysis yields a quantitative look at both the size gradient in plateau borders as the …
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Engineering arterial substitutes that recapitulate vessel microstructure and mimic native physiological responses
… sheets with controlled anisotropy using a flow-focusing approach. This strategy represents the first of its kind to generate anisotropic collagen sheets with control over nano- and macro-molecular properties. Next, controlled assembly of vascular cells and free-standing collagen sheets …
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Microfluidic encapsulation of carbon capture materials
… and carbonate-rich solutions. Specifically, a flow-focusing microfluidic device was used to create double emulsions composed of a photocurable polymeric shell that surrounds an aqueous carbon dioxide absorbent core. After droplet formation, the shell was cured using ultraviolet light to form …
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Response of Electrified Micro-Jets to Electrohydrodynamic Perturbations
… through a small orifice, ~50 micrometer flow focused jets, and ~20 micrometer electrified Taylor-cone jets. The transverse perturbations enable systematic triggering of varicose and whipping instabilities, and consequently a wide range of remarkable phenomena emerge. For inertial jets …
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Design and evaluation of novel microencapsulation technologies to enhance delivery of Ciclosporin
… the utility of PDMS and silicon microfluidic flow focusing devices (MFFDs) to produce PLGA-based microparticles. The formation of uniform droplets was dependent on the surface of PDMS remaining hydrophilic. However, the durability of PDMS was limited to no more than 1 hour before wetting of …
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Experimental and numerical study of temperature-actuated droplets within microfluidics
… and behavior when heat is applied to a flow-focusing microstructure under variable flow conditions. The study focused on two main topics; (1) Studying the effect of temperature variation on the behavior water droplets emulsified in mineral oil when heat is applied to the downstream …
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Intelligent design of microfluidic components for Newtonian and complex fluid systems
… non-Newtonian fluids in shear and extensional flows. Biomimetic principles and shape optimisation methods are employed to propose new designs for single-phase fluid flow. Furthermore, the single-phase numerical solver is extended to cope with two-phase systems, thus paving the way for new …
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Lab-on-a-Chip Integration of Size-based Separation Techniques for Isolation of Bacteria from Blood
… lateral displacement technique and the Dean flow focusing methods. Through these approaches blood cell reduction prior to bacteria isolation can be achieved, thereby increasing the overall sample volume that may be processed by the system. Additionally, a miniaturized hydrocylone capable of …
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Self-assembly of inorganic nanoparticle amphiphiles for biomedical applications
… we reported that the use of a microfluidic flow-focusing device for the self-assembly of JVs that can act as vesicular motors. The vesicles can be used to encapsulate active compounds, and the release of this payload can be effected using near-infrared light. This systematic study will help …
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A microfluidic platform for combinatorial synthesis and optimization of targeted polymeric nanoparticles for cancer therapy
… anti-solvent (i.e. water) using 3D hydrodynamic flow focusing where NPs self-assemble after complete mixing. With the microfluidic platform, a library of 100 NPs with different sizes (15-200nm), charge (-30 to +30mV), surface chemistry (i.e. PEG coverage), surface ligand density (0-2.510⁵ …
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Design and synthesis of microcapsules using microfluidics for autonomic self-healing in cementitious materials
… self-healing in cementitious materials. A flow-focusing microfluidic device was used to produce double emulsions to be selectively photopolymerised to generate a core-shell structure. Subsequently, the physical triggering was assessed by embedding the produced microcapsules in cement paste, …
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