Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"flash nanoprecipitation"”.
-
Design, Synthesis, and Characterization of Magnetite Clusters using a Multi Inlet Vortex Mixer
… and control of size distributions using flash nanoprecipitation. First, the mixer was tested using β-carotene as a model compound to form nanoparticles stabilized with an amphiphilic triblock copolymer poly(propylene oxide)-b-poly(ethylene oxide) (F127) at different Reynolds numbers and …
-
Nanoparticles Targeting at Inflammation Site
… formulation, PEG-PCL-NanoPaz-t, produced via flash nanoprecipitation followed by spray drying. This scalable approach achieved over a 9,000-fold increase in production rate and maintained the therapeutic efficacy of pazopanib in a canine OA model, demonstrating extended pain relief and …
-
Small Solutions to Big Problems: Design and Synthesis of Nanoparticles for Biomedical Applications
… to bridge the knowledge gap regarding the use of flash nanoprecipitation (FNP) for nanoparticle synthesis. FNP is a scalable nanoparticle fabrication method that produces small, well-defined nanoparticle populations through rapid, turbulent mixing of multiple solvent streams. This work elucidates …
-
Synthesis and Characterization of Drug-Containing, Polysaccharide-Based Nanoparticles for Applications in Oral Drug Delivery
… by a rapid precipitation process known as flash nanoprecipitation and the formulation process and properties of nanoparticles were investigated. In this thesis, several novel cellulose derivatives and a pullulan derivative were studied. Among these polymers, carboxymethyl cellulose acetate …
-
Polymer Nanoparticle Characterization and Applications for Drug Delivery
… in PLGA were explored. It was found that flash nanoprecipitation increased loading of αCT1 in the particles by 1-2 orders of magnitude compared with the double emulsion method. Particles released αCT1 over three weeks and were non-cytotoxic.
-
Amphiphilic Poly(2-isopropyl-2-oxazoline)-block-poly(lactide) Nanoparticles as Drug Delivery Vehicles
… efficiencies and slower release rates. Flash nanoprecipitation method (FNP) was also used to prepare the same nanoparticles with and without encapsulated curcumin. In addition to the encapsulation efficiencies, sizes of the nanoparticles were determined via dynamic light scattering …