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Showing 1 to 9 of 9 for “"flagellar assembly"”.
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Defining the molecular composition and organisation of Transition fibres in Trypanosoma brucei and their roles in flagellar assembly and length control
… docking and regulate the trafficking of intraflagellar transport (IFT) proteins required for flagellar assembly. Transition fibres are present in all ciliated organisms yet only a handful of TF proteins have been identified in mammalian cells. We hypothesise that there are a number of …
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Probing the assembly of the <em>Bacillus subtilis</em> flagellum and its role in signal transduction.
… a function to YvyG as an orthologue of a flagellar type 3 secretion system chaperone that is essential for flagellar assembly. Crucially this work provides further evidence that the <em>B. subtilis</em> flagellum is regulated by both conserved and species-specific means. These experiments …
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The Development of Di-N-Acetyl-L-Pyranosides for the Synthesis of Pseudaminic Acid and 8-epi-Legionaminic Acid
… These sugars are found to be crucial to flagellar assembly and are thus attractive targets for raising an immune response against. By retrosynthetic analysis, we hypothesized that using L-sugars as starting materials for synthesis of the key hexose intermediates was a novel and practical …
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Phenotypic variation and bistability within flagellar gene network in Salmonella Typhimurium
… among at least 17 operons are involved in flagellar biogenesis and chemotaxis. One of the critical features of this process is coupling of the gene expression to assembly. Like flagellar assembly, gene expression also proceeds in a sequential manner. Availability of nutirients in the …
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The Role of Periplasmic Disulfide Bond Status in the Regulation of the Salmonella SPI1 Type Three Secretion System
… response is dependent on both the flagellar protein FliZ and the RcsCDB system, which also affects fliZ transcription. Thus, the status of disulfide bonds in the periplasm affects expression of the SPI1 system indirectly via regulation of the flagellar apparatus. RcsCDB can also …
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The role of transition fibre proteins in regulating CEP164C assembly and localisation to the flagellum in the African Sleeping Sickness parasite Trypanosoma brucei
… CEP90, regulate CEP164C recruitment to control flagellar assembly and length in Trypanosoma brucei, a paristie responsible for African trypanosomiasis. We focus on proteins within the transition fibres of the basal bodies, essential for flagellum assembly and cell division in the procyclic …
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Análisis multi-ómico en gónadas de Solea senegalensis perspectivas moleculares de la reproducción en individuos salvajes y F1
… of proteins related to spermatogenesis, flagellar assembly, and sperm–egg interaction. These findings confirm the presence of a molecularly based testicular dysfunction associated with incomplete maturation and reduced fertilization competence under farming conditions. Integration of …
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Molecular, biochemical and functional analysis of kinesins in Leishmania mexicana
… is one of the model organisms to study flagellar assembly. Here, we used L. mexicana as a model to investigate flagellar kinesin motor proteins. Kinesins are a large superfamily (KIFs). More than 15 kinesin families were classified by phylogenetic analysis (Wickstead et al., 2006). …
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Regulation and switching in bacterial gene expression networks in response to nutrients
… utilization networks in Escherichia coli and flagellar assembly networks in Salmonella enterica serovar Typhimurium in response to nutrients. Firstly, chapters 3-5 focus on sugar utilization pathways in E. coli. Bacteria rely on utilizing various carbon sources for growth and survival. When …