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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 32 for “"first-degree relatives"”.

  1. Empiric risk to first-degree relatives of Alzheimer disease patients

    Hirst, Clinton G.University of British Columbia1993

    … estimates were generated and evaluated for 1867 first-degree relatives of 338 Alzheimer Disease (AD) index cases and 1873 first-degree relativesof 351 non-cognitively impaired, non-demented elderly controls. A cumulative lifetime risk of 26.73 ± 4.42% for first-degree relatives of AD cases, while …

    ubc Repository record

  2. Defining Microbiome Stability in First-Degree Relatives of Inflammatory Bowel Disease Patients

    Koentgen, SabrinaUNSW, Sydney2026

    … manifestation and progression of the disease. In first-degree relatives (FDR) of IBD patients risk is notably increased, yet most FDRs don’t progress to develop the condition despite sharing genetic and environmental risk factors. Limited research has sought to characterise the microbiome in this …

    unsw Repository record

  3. Boundaries of the cognitive phenotype of autism: social cognition and central coherence in young people with autistic traits and their first degree relatives

    Best, Catherine2007

    Autism is a behaviourally defined disorder. The impairments in social communication and repetitive behaviours are individually non-specific. The disorder has indistinct boundaries both with other psychiatric disorders and with normal personality types. At the cognitive level, groups of people with …

    edinburgh Repository record

  4. Inhibition of Gamma Oscillations as a Neurophysiological Endophenotype of Schizophrenia

    Radhu, Natasha2015

    … a potential endophenotype of SCZ. Objectives The first objective was to quantitatively assess transcranial magnetic stimulation (TMS) motor cortex measures of inhibition and excitation in obsessive-compulsive disorder (OCD), major depressive disorder (MDD) and SCZ, as a meta-analysis. The second …

    toronto-retro Repository record

  5. ΣΥΜΒΟΛΗ ΕΙΣ ΤΗΝ ΜΕΛΕΤΗΝ ΤΟΥ ΠΡΟΣΤΑΤΕΥΤΙΚΟΥ ΡΟΛΟΥ ΤΩΝ ΥΨΗΛΗΣ ΠΥΚΝΟΤΗΤΟΣ ΛΙΠΟΠΡΩΤΕΙΝΩΝ (HDL) ΕΙΣ ΕΞ ΑΙΜΑΤΟΣ ΣΥΓΓΕΝΕΙΣ ΤΩΝ ΕΠΙΖΗΣΑΝΤΩΝ ΕΞ ΕΜΦΡΑΓΜΑΤΟΣ ΜΥΟΚΑΡΔΙΟΥ

    Τσουμάνης, ΦώτιοςNational and Kapodistrian University of Athens1986

    … PAIRS OF SURVIVORS OF MYOCARDIAL INFARCTION AND FIRST DEGREE RELATIVES OF THE SAME SEX AND WITH COMPARABLE AGE. THE T-TEST WAS USED AND WE COMPARED THE MEASUREMENTS OF THE TOTAL CHOLESTEROL, HDL-CHOLESTEROL, AND THE DIFFERENCE TOTAL C -- HDL-C. THE RESULTS SHOWED THAT THE HDL-C IS INCREASED …

    greece Repository record

  6. Valutazione del rischio genetico di comportamento suicidario nel disturbo bipolare: analisi di 737 pedigrees

    MANCHIA, MIRKOUniversità degli Studi di Cagliari2012

    … in 737 families of probands with MAD with 4,919 first-degree relatives (affected and unaffected). Cox proportional hazard regression models and logistic regression models were used to investigate the role of several clinical covariates on the risk of MAD, BD and suicidal behavior. Results: The …

    cagliari Repository record

  7. Environmental factors affecting the risk of breast cancer

    Taylor, Cheryl MVictoria University2007

    … history of the disease especially if there are first degree relatives affected, history of benign breast disease, age at menarche, age at menopause, number of full term pregnancies and the use of hormone therapies. Some researchers suggest that as the incidence of breast cancer is rising, and …

    vu-aus Repository record

  8. Studies in cardiomyopathy: looking beyond the familiar

    Ntusi, Ntobeko A BDivision of Cardiology2016

    … hypertrophic cardiomyopathy (HCM) patients and first degree relatives seen in a specialist cardiogenetic clinic at Tygerberg Hospital, who underwent cardiovascular magnetic resonance (CMR) imaging at Groote Schuur Hospital.

    cape-town Repository record

  9. Breast Cancer Risk For Female Relatives of Male Breast Cancer Patients With Negative Brca1/2 Testing

    Martin, Emily, <p>0000-0003-3857-0562</p>2022

    … if prevalence of breast cancer among female relatives is higher when there is a family history of male breast cancer in the context of uninformative <em>BRCA1 </em>and <em>BRCA2 </em>testing. This information may aid in the process of risk assessments for patients and their families following …

    uthsc Repository record

  10. Neural Indicator of Altered Mismatch Detection Predicts Atypical Cognitive-Perceptual Experiences in Psychotic Psychopathology

    Pokorny, Victor2022

    … disorder (BP), 90 healthy controls and 72 first-degree relatives of SCZ (SREL) were studied. We used principal components analysis to decompose averagereference 64-channel subject-level ERPs. Results: Altered attentional modulation was evident in SCZ at early (N1 factor) and late (P3 …

    umn Repository record

  11. Communication In Family Members With A Rare APC Mutation

    Mann, Megan Michelle

    … Patients are communicating more with their first-degree relatives than with their more distant relatives. Health care professionals should review strategies of communication of genetic risk information to at-risk family members with their patients.</p>

    south-carolina Repository record

  12. Evaluation of Recurrence Risks For Left-Sided Cardiac Lesions

    Swain, Sarah2011

    … parents of LSL probands. Lastly, among affected first-degree relative pairs (i.e. siblings, parent-offspring), the majority (65%-70%) were both affected with a LSL. Defect specific concordance rates were highest for AS/BAV. Together, these findings suggest that over the past 20 years with …

    uthsc Repository record

  13. A Multifactorial Study of Factors Influencing Self-Health Behaviors in Dementia

    Malkin, Elizabeth2024

    … questions about knowledge of risk factors and degree of closeness to family members with dementia to determine whether (1) more closely related relatives (first-degree relatives) and those close to the affected individual (caregiver) will have greater perceived susceptibility and motivation to …

    national-louis Repository record

  14. A comparative cost analysis of two screening strategies for colorectal cancer in Lynch Syndrome in a tertiary hospital, South Africa

    Johnson, YasminaHealth Economics Unit2017

    … 01 November 2014 and 30 October 2015, and their first degree relatives (high risk relatives) were evaluated according to Strategy 1 and Strategy 2. Total costs per strategy were estimated and compared. Sensitivity analyses were performed on adherence rates to colonoscopy, positivity rates of …

    cape-town Repository record

  15. The continuum of response to blood/injury stimuli as demonstrated by autonomic reactivity and affect

    Rock, Christina M.Virginia Tech1995

    … and feeling faint, with B/I stimuli; and more first degree relatives with similar experiences.

    vt Repository record

  16. The Relationship of Cognitive, Emotional, and Interpersonal Factors to Screening and Health­Promoting Behaviors Among Sisters of Breast Cancer Patients

    Hartman, Sheri JacobsDigital Commons @ University of South Florida2007

    … cancer history and age, little research with first-degree relatives of cancer patients has focused solely on sisters. To address this issue, the current study examined sisters screening and health behaviors and the predictors of these behaviors. In accordance with the Parallel Processing …

    usf Repository record

  17. Impact of family history of premature coronary disease on carotid ultrasound and coronary calcium findings

    Taraboanta, CatalinUniversity of British Columbia2008

    First degree relatives (FDRs) of subjects with early onset of coronary heart disease (CHD) have higher risk of developing cardiovascular disease. We verified early CHD by angiography in the index patients and extensively phenotyped their FDRs to investigate the relationship of traditional and …

    ubc Repository record

  18. A Comparison of Inpatient and Outpatient Treatment Programs for Bulimia Nervosa

    Richter-Reno, Claudette M.

    … group, however, had significantly more first degree relatives who abused alcohol and/or drugs than the inpatient/outpatient group. Further analyses revealed that both groups significantly decreased their reported binge frequency, purge frequency, BDI scores, and EDI Drive for Thinness …

    nodak Repository record

  19. Genome-Wide Association Analysis of Major Depressive Disorder and Its Related Phenotypes.

    Aragam, Nagesh Ramarao2011

    … compared to men) and is highly heritable among first degree relatives. Several novel genetic loci were identified to be associated with neuroticism and age at onset. Gender differences were found in genetic influence of neuroticism. These findings offer the potential for new insights into the …

    etsu Repository record

  20. The Genetic Architecture of Alopecia Areata

    Petukhova, Lynn Meredith2013

    … research, including increased risk of disease in first degree relatives, twin studies, and more recently, our initial family-based linkage study and genome wide association study (GWAS) in a cohort of unrelated individuals. Importantly, our GWAS identified a set of 16 statistically independent …

    columbia-diss Repository record

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