"first procaspase activating compound (PAC-1)" · 2 results · Global ETD Search

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Showing 1 to 2 of 2 for “"first procaspase activating compound (PAC-1)"”.

Improving the process synthesis, potency, and pharmacokinetics of the anticancer compound PAC-1

Roth, Howard StevenUniversity of Illinois at Urbana-Champaign2015

Embargo set by: Seth Robbins for item 89526 Lift date: 2017-09-29T21:08:35Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD system

uiuc Repository record for Improving the process synthesis, potency, and pharmacokinetics of the anticancer compound PAC-1 (opens in a new tab)
Evaluation of therapy for canine intracranial neoplasia using PAC-1, a novel and potent procaspase-3 activator

Schlein, Lisa JanelleUniversity of Illinois at Urbana-Champaign2018

… resection and limiting therapeutic options. PAC-1 is a novel, blood-brain barrier penetrant, pro-apoptotic small molecule activator of procaspase-3 (PC-3), with orphan drug status for the treatment of human glioblastoma multiforme. PC-3 is frequently overexpressed in malignantly transformed …

uiuc Repository record for Evaluation of therapy for canine intracranial neoplasia using PAC-1, a novel and potent procaspase-3 activator (opens in a new tab)