Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 78 for “"firing rate"”.
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Motor unit firing rate control of agonist skeletal muscle during voluntary isometric and shortening contractions with limb movement
… controlled by time- and recruitment-dependent firing rate patterns. Single motor unit (MU) activity reflects the final efferent neural drive to the muscle, yet the underlying neural control of movement at the MU level is not well understood. Using intramuscular electromyography single MU …
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Encoding of periodic skin stimuli by spinal dorsal horn neurons
… somatosensory nuclei, including analyses of firing rate and periodicity. Firing rate profiles, phase vectors, histograms and power spectra were used to quantify the responses. The analyses indicate that for most cells, firing rate is adequate to encode stimuli at 50 Hz and below, but …
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Characterization of Thermosensitive Preoptic Neurons in the Green Sunfish, Lepomis Cyanellus
… which comprised 4% of the total, had low firing rates (approximately 5/second) at 25(DEGREES)C brain temperature. Firing rate increased exponentially with increasing brain temperature and remained constant at brain temperatures below 25(DEGREES)C. Type 1 neurons discharged in a continuous, …
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Influence of Pramipexole on Probability Discounting and Ventral Pallidal Function: Assessments in Parkinsonian-Like Rats
… and/or chronic pramipexole treatment. We incorporated an animal model of PD in this study to determine if a PD-like brain state alters the response of pramipexole in the discounting paradigm. The final series of studies focused on determining if a limbic brain region involved in reward-related …
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Functional Identification of Nucleus Tractus Solitarius (NTS) Barosensitive Neurons: Effect of Chronic Intermittent Hypoxia (CIH)
… we showed that baroreflex control of heart rate (HR) (baroreflex sensitivity) is reduced in CIH rats. While afferent function and HR in response to vagal efferent stimulation are enhanced, the effect of CIH on the central components, in particular NTS, is still not completely understood. …
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The Neuromuscular and Mechanical Control of the Knee Joint in Patellofemoral Pain Sufferers
… Grouped Tape Response: The mean motor unit firing exhibited an increase in the VM firing rate and a decrease in the VL firing rate within the tape condition, across both subject groups, suggesting a modification in the load bias across the Vasti muscles. The common drive, a physiological …
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Optogenetic disruption of memory-drive, oculomotor behavior in the non-human primate
… remembered locations. FEF neurons increase their firing rate during the three epochs of the memory-guided saccade task: visual stimulus presentation, the delay interval, and motor preparation. It is unclear, though, whether FEF activity during each epoch is necessary for memory-guided saccade …
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Activity-Dependent Regulation of Inhibition from Different Inhibitory Subtypes
… activity, in the form of action potential firing, is critical in the maturation and maintenance of neocortical circuitry. A negative feedback mechanism by which neuronal circuits adapt to changing levels of average activity on a time scale of hours to days is known as homeostatic …
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The role of short term synamptic plasticity in temporal coding of neuronal networks
… detection means a target neuron has a higher firing rate when it receives simultaneous inputs from different neurons as opposed to inputs with large phase delays. This property is used by birds in sound localization. When there is no plasticity from the inputs, the firing rate of the neuron, …
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Complex Acoustical Feature Representation in the Zebra Finch Caudomedial Neostriatum (Ncm)
… a primary analysis of the representational strategies available in the neurophysiological responses of neurons in the NCM. We developed a pair of matched auditory stimuli that share the same acoustic envelope (acoustic contour), but differ in their spectral organization (acoustic texture). We …
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The Pedunculopontine Nucleus: A Potential Site of Respiratory Modulation During Muscle Contraction and Hypoxia
… employed in the first group of studies to demonstrate that individual PPN neurons exhibited increases in firing rate during activation of muscle reflex pathways during static muscle contraction. Activation of PPN neurons was shown to have functional significance in that microinjections of …
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Investigation of the Signaling Mechanisms of the Pineal Hormone Melatonin in the in Vitro Rat Suprachiasmatic Nucleus
… the SCN exhibits a 24-h oscillation in ensemble firing rate that peaks at midday. Melatonin application to the brain slice during times restricted to subjective dusk and dawn advances the peak in firing rate by up to 4 h. This study showed that the shift induced by melatonin is dependent upon …
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Windows in the clock: An in vitro study of melatonin action and signal transduction in the suprachiasmatic circadian pacemaker
… brain slice preparation, we have demonstrated a direct resetting of the SCN pacemaker's rhythm of ensemble neuronal firing rate in response to exogenous melatonin treatment. This effect depends upon the phase of the pacemaker at the time of treatment: maximal responses to 1 hr treatment …
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Error correction in the hippocampal-medial-entorhinal cognitive map
… clues have a complex influence on their firing patterns. In this thesis, I investigate the effect of environmental landmarks on error correction in spatially modulated cells during one dimensional navigation in a virtual reality environment, using in vivo chronic multi-tetrode recordings …
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Prefrontal coding of naturalistic working memory: Mechanisms during normal maintenance and modelled disease
… the pathophysiology of schizophrenia, I demonstrate drastic deficits in WM performance. The decrease in performance is related to differential effects on putative excitatory and inhibitory neurons. Inhibitory neurons decrease their firing rate for their preferred location after ketamine …
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Fatty acid ethanolamides pinpoint nicotinic receptors and modulate neuronal excitability through nuclear receptor PPARα
… stimulation of VTA dopamine (DA) neuron firing rate through the peroxisome-proliferator-activated receptor-α (PPARα) and to elucidate their mechanism of action in an in vitro brain slice preparation. 2) To determine whether there is an interaction between PPARα and nAChRs in VTA DA cells: …
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Effects of neuronal correlations on population decoding and encoding models
… factors. The performance of these models on firing rate prediction (encoding) and population decoding are studied. Our analyses show a significant beneficial effect of pairwise correlations on encoding models, with much of this benefit being explained by the global noise models. However, the …
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A prefrontal source of visual target enhancement in the macaque area V4
… neuronal activation in the VPA is necessary for firing rate increases related to target selection in V4. KEYWORDS: feature attention, visual search, muscimol, neurophysiology
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The Role of Orexin in Modulating Locomotion
… showed a considerable increase in the firing rate of motoneurons, further suggesting orexin’s involvement in the locomotor circuitry.
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