Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"finasteride"”.
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Finasteride lowers cholesterol in humans and delays atherosclerosis progression in Ldlr-/- mice
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2023-12-01
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La clozapine et les neurostéroïdes dans la modulation de comportements associés au suicide dans un modèle murin de schizophrénie
… behaviors is mediated through NS modulation. Finasteride, a 5α- reductase inhibitor was injected alone or before clozapine treatment in controls (ctl) and THMS mice. Prepulse inhibition (PPI), resident intruder test (RI) and exploratory behaviors (EB) were performed to assess the sensorimotor …
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Combination of Dietary Tomato and Broccoli Powders Are Effective Growth Inhibitors of Dunning R3327-H Prostate Adenocarcinomas
… quantified in the liver, prostate, and tumors. Finasteride significantly decreased expression of 5-alpha-reductase-II, Bcl-2, and IL-6 in tumors. IL-6 was reduced in high lycopene and broccoli, P=0.05, and TNF-alpha was lower with low lycopene, P=0.05. Overall, the combination of tomato and …
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Testosterone’s regulation of the HPA axis differs for adolescent and adult male rats
… treated with fadrozole (aromatase inhibitor), finasteride (5a-reductase inhibitor), flutamide (androgen receptor antagonist), or vehicle (VEH). Higher CORT concentrations after restraint were found in P45 than in P75 only among VEH rats. Among P45 rats, CORT levels were higher in VEH than in …
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Ruolo dei neurosteroidi nella modulazione dopaminergica
… antidopaminergic effects. The 5AR inhibitor, finasteride (FIN), is currently approved for the therapy of benign prostatic hyperplasia and androgenic alopecia. We found that, in rodents, FIN attenuates the severity of behavioral manifestations induced by dopaminergic agents, including deficits …
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Development of a novel, clinically-relevant model for investigating factors that stimulate human hair growth
… unlike the 5¿-reductase type 2 inhibitor finasteride (40ng/ml). Immunohistochemistry demonstrated androgen receptor and 5¿-reductase type 2 proteins in both follicle types, while quantitative real-time PCR and gene microarray analysis detected their increased gene expression in …
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Lycopene, Selenium, Vitamin E and Prostate Cancer
… no effect on gene expression but castration or finasteride-treatment did lead to expression alterations, suggesting that these genes are androgen-responsive.
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Endogenous neurosteroid actions at GABAA receptors during neuronal development
… synthesis using the 5a-reductase inhibitor, finasteride, or treating the brain slice with the steroid-scavenger molecule, ?-cyclodextrin (?-CD), results in significantly faster mIPSC decay times between P7 and P10 in VB and L2/3 neurones. These results provide the first indication that an …