Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"filamentous growth"”.
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Protein kinase A-dependent phosphorylation and degradation of CDK8 : implications for yeast filamentous growth
… to nitrogen depravation and has been termed filamentous growth, as cells form filament-like projections away from the center of the colony. The regulation of this response is under the control of the well-characterized MAPK and cAMP pathways. Previous work showed that Cdk8p phosphorylated a …
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Analysis of Nitrogen starvation induced filamentous growth and characterization of putative essential genes in the human fungal pathogen, Candida albicans
1. Zusammenfassung Candida albicans ist ein opportunistisch pathogener Hefepilz, der sowohl oberflächliche Infektionen der Schleimhaut als auch lebensbedrohliche systemische Infektionen hervorrufen kann. Obwohl die Fähigkeit von C.albicans Infektionen auszulösen weitgehend vom Immunstatus des Wirts …
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RGA2, a putative rho-type GTPase-activating protein, is regulated by the transcription factor Tec1 during filamentous growth of Saccharomyces cerevisiae
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Biology, 1999.
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Post-transcriptional coordination by an RNA-binding protein
… processes in response to various stimuli. Filamentous growth in Saccharomyces cerevisiae is a morphogenetic switch that occurs in response to nitrogen starvation and requires alterations in cell growth, cell cycle, and cell wall functions. Tyl element retrotransposition is also induced …
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Molecular Analysis of Phenotypic Diversity in Human Fungal Pathogens
… Further, I showed that C. auris is capable of filamentous growth in response to Hsp90 depletion or inhibition. Transcriptomic analysis upon HSP90 depletion showed that filamentous growth is associated with upregulation of putative cell wall associated genes. Overall, my research provides key …
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The effect of fixed film pretreatment on activated sludge stability during the treatment of cellulose acetate wastewater
… in terms of Sludge Volume Index and had less filamentous growth than the CAS system. The TF pretreatment confirmed its ability to act as a roughing filter. During the study, it reduced the organic loading on the AS system by 26 to 43 %, oxygen requirement of AS system by 38 to 62 %, the …
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The Effect of Slowly Biodegradable Carbon on the Morphology, Integrity and Performance of Aerobic Granular Sludge
… of the granules. The granule surface had more filamentous growth and a more porous structure. AGR fed with a 1:1 particulate:soluble COD feed also demonstrated reduced nitrogen and phosphorous removal (78 and 81%, respectively). Moreover, only 75% COD removal was accomplished. Microscopy …
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Mechanisms underlying cell-to-cell diversity in clonal populations of yeast
… adhesion to and invasion of inert surfaces, and filamentous growth. In this thesis, I discuss chromatin modifying proteins that localize to the FLO10 and FLO11 promoters and act in trans to affect transcription and silencing at these promoters. I describe the results of genome-wide screens to …
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The effect of high purity oxygen on the activated sludge process
… concentration is susceptible to takeover by filamentous microorganisms. A model was proposed to explain this phenomenon. Results also suggest that it is not the use of oxygen which is responsible for differences in substrate removal rates and yield observed between air and oxygen activated …
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An examination of biological phosphorus removal using bacterial counting and poly-β-hydroxybutyrate analysis in batch and continuous flow systems
… into the aerobic zone, which stimulated filamentous growth, and eventually caused a lack of PHB formation. All of these factors contributed to a loss of excess biological phosphorus removal at the low temperature.
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Factors affecting the growth of Nostocoida limicola II and other filamentous microorganisms in activated sludge systems
… to uncover factors responsible for the prolific growth of various filamentous microorganisms in the bulking activated sludge at the Hoechst Celanese wastewater treatment plant. First, futile attempts were made to isolate the filamentous bacterium, <i>Nostocoida limicola II</i>, from activated …
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Conclusions About Functional Relationships Between the Candida Albicans *Als Proteins Drawn From Analysis of ALS Gene Expression Patterns
… disseminated candidiasis and across budding and filamentous growth of cultured cells. Methods of detection of gene expression included reverse transcriptase polymerase chain reaction (RT-PCR) analysis of RNA, and flow cytometry and immunohistochemical detection of green fluorescent protein …
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Identification of substrate proteins of FtsH during sporulation of Bacillus subtilis
… exhibits a pleiotropic phenotype such as filamentous growth, sensitivity towards heat, osmotic shock and cells are unable to sporulate. Recently, it has been shown that ftsH knockout cells fail to entry sporulation stage II due to lack of a sufficient amount of Spo0A~P and the first …
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An investigation into marine biofouling and its influence on the durability of concrete sea defences
… fibres was also studied. It was found that algal growth quickly developed at the interface of inclusions within the matrix and that power washing with the use of Dairy Hypochlorite to remove this accelerated wear, leading to significant mass loss. It was also observed that bacterial growth within …
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Die frühe Infektionsphase von Ustilago maydis
… cascades of regulatory processes. These control filamentous growth, penetration of the plant surface, growth inside the plant and induction of galls. The aim of this work was the isolation of genes regulated by the bW/bE heterodimer that play a role during early pathogenic development. For this …
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Screen design for Borrelia burgdorferi lipoprotein secretion pathway components using periplasmic protein capture and suppressor mutations
… binding peptide tag yielded significant filamentous growth as well as overall growth defects in E. coli, and no B. burgdorferi transformants were recovered.
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Function of the ATP-dependent Metalloprotease FtsH during sporulation in Bacillus subtilis
… are sensitive to salt and heat shock, exhibit filamentous growth, are difficult to be transformed and are almost unable to sporulate. Despite the severe phenotype caused by the absence of the ftsH gene, the precise functions of this protein remained unclear. This PhD thesis presents data to …
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Regulation of Growth and Development by the Small GTPase Cdc42p and the Transcription Factor Tec1p in <i>Saccharomyces cerevisiae</i>
Die Bäckerhefe Saccharomyces cerevisiae ist ein dimorpher Pilz, der in verschiedenen Wachstumsformen vorkommen kann. Stickstoffmangel löst in diploiden Zellen den Übergang vom Wachstum in der einzelligen Hefeform zu einer multizellulären, filamentösen Form aus. Diese Wuchsform wird als …