Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"fibrin clot formation"”.
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Fibrin Formation and Dissolution in the Progression of Amyloid-Beta Pathology in Alzheimer's Disease
… neurovascular damage in AD mice, and showed that fibrin deposition potentiates these processes. We then found that Aβ binds to fibrinogen and alters fibrin clot formation. Clots formed in the presence of Aβ have an abnormal structure and are resistant to degradation by fibrinolytic enzymes. We …
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Design and performance of hemostatic biomaterials for managing hemorrhaging
… being developed that: (1) generate artificial clots independent of the coagulation cascade or (2) interact with blood components to accelerate or otherwise improve coagulation processes. Hemostatic materials designed for internal bleeding can save lives in the battlefield, en route to emergency …
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Mechanical modeling of tissue response during early stage entubulated peripheral nerve regeneration
… from transected nerve stumps coagulates into a fibrin matrix within the entubulated space by the end of the first week. Over the following four weeks, two distinct groups of cells migrate into the fibrin-filled gap. The first group consists of fibroblasts which differentiate into the …
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Characterization of OmpT: An outer membrane vesicle protease Escherichia coli that attenuates blood coagulation.
… FVa profoundly enhances thrombin generation and fibrin clot formation as part of prothrombinase. The fibrin clot immobolizes the pathogen and allows the immune system to target and destroy the bacterium. Our research has shown that pathogenic Escherichia coli O86a:K61 secretes the protease OmpT …