Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"fetal tissue"”.
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Accurate noninvasive monitoring of fetal tissue oxygenation level
Fetal blood oxygenation level serves as a critical indicator of fetal health throughout pregnancy and labor. However, existing clinical devices predominantly employ invasive techniques, posing risks to both the fetus and the mother. To address this concern, we present a noninvasive method for …
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Fetal tissue containing the suprachiasmatic nucleus restores circadian rhythms in old rats
… the major circadian pacemaker in mammals. When fetal tissue containing the SCN is transplanted into young rats whose circadian rhythms have been abolished by SCN lesions, the rhythms gradually reappear. The anatomical and electrophysiological properties of the SCN undergo changes with age. Such …
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A Study of Fetal Tissue Implantation for the Treatment of Parkinson's Disease: Can Self-Efficacy and Social Support Predict Physical Functioning and Perceived Treatment?
… have comprehensively explored the benefit of fetal tissue implantation in Parkinson's disease (PD) patients. This type of investigation is necessary to better understand how and why some participants in a double-blind investigation of fetal tissue implantation for PD improved following the …
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A Longitudinal Study of Fetal Tissue Transplantation Surgery for the Treatment of Parkinson's Disease: Can Quality of Life and Optimism at Baseline Predict Patient Outcome 10 Years Later?
… trial to investigate the effectiveness of fetal tissue transplantation for the treatment of advanced PD. The authors of that study examined the effects of the surgery across the dimensions of physical and neurological functioning. A quality of life (QoL) study was conducted to determine if …
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Longitudinal Perspective of Participation in a Double Blind Placebo Surgery Trial
… 2001, Freed et al. investigated the effects of fetal tissue transplantation in participants with PD by conducting a double-blind sham-controlled surgery trial. The quality of life (QoL) study was conducted concurrently by McRae et al. (2004) in order to determine whether QoL improved in …
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The effect of non-weight-bearing exercise and protein intake during pregnancy on maternal and fetal zinc content in the Sprague-Dawley rat
… protein intake during pregnancy on maternal and fetal zinc status in the rat, one hundred and seventy-nine pregnant Sprague-Dawley rats were divided into four groups; sedentary-standard protein diet, sedentary-high protein diet, exercising-standard protein diet and exercising-high protein diet. …
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Executive Regulation of Abortion During the Reagan-Bush Years
… the 1984 "Mexico City Policy," the 1988 Fetal Tissue Research Funding Ban," and the 1988 "Gag Rule" illustrates how regulation was created, implemented, legitimized and sustained all through the powers of the Reagan-Bush administrations. These regulations violated legal standards and …
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CELL REPLACEMENT THERAPY FOR PARKINSON’S DISEASE: The importance of neuronal subtype, cell source and connectivity for functional recovery
… reform damaged neuronal circuitry? Use of human fetal tissue raises several ethical issues, but are there alternative cell sources that can substitute effectively? The aim of this thesis was to understand how particular factors such as neuronal content, placement and cell source, affect …
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Generation of midbrain dopaminergic neurons in vivo and in vitro: the role of Neurogenin2
… where dopaminergic neuroblasts derived from fetal ventral mesencephalon (VM) are transplanted to the striatum, may be an alternative to pharmacological treatment of PD patients. The limited access and ethical concerns with using fetal tissue have prompted the use of stem cells as a renewable …
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Investigating thyroid hormone transport and regulation in chorionic somatomammotropin RNAi models of intrauterine growth restricted pregnancies
… a decrease of thyroxine levels in maternal and fetal circulation. Transthyretin (TTR) is a TH binding molecule produced by trophoblast cells that preferentially binds T4 and may shuttle T4 through the placenta. It was our objective to better understand thyroid hormone transport during late …
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Adult behaviour and cerebral cell densities after maternal or post-weaning consumption of an obesogenic diet in mice
… dams were killed at day 18.5 of pregnancy for fetal tissue collection while the rest delivered naturally, with litters reduced to 6 at postpartum day 2. Behaviour of male and female 12 weeks old offspring was tested using an elevated plus maze (EPM for anxiety), open field (for anxiety and …
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Providing the option to look: Independent clinic workers' approaches to fetal viewing practices
This Dissertation was approved for publication on 2016-07-12 at 13:09.
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Intracellular signaling cascades in the dopaminergic specification of fetal mesencephalic neural progenitor cells.
Neural stem (progenitor) cells (NPCs) from fetal tissue are an ideal transplantable cell source. They divide rapidly, are able to generate cells of all three neural lineages and do not divide uncontrolled once transplanted into a host organism. To obtain large quantities of cells for …
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A Reductionist Approach to Modeling Human Corticogenesis
… the availability of non‐human primate and human fetal material, the longer timescale of developmental processes, as well as the ethical considerations involved preclude direct experimental observations in both these organisms. However, human pluripotent stem cells (hPSCs) allow a window into …