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Showing 1 to 3 of 3 for “"fetal kidney"”.
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Impact of Differentiation Status of Kidney Progenitors In Wilms Tumor Development
… in children. It is an embryonic cancer of the kidney and is thought to arise from undifferentiated renal mesenchyme. However, the differentiation status of cells in the mesenchyme that can give rise to Wilms tumors is unknown. Gene expression analysis of a large panel of Wilms tumor patients …
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Identification of Familial Wilms Tumor Predisposition Genes Using Whole Genome Sequencing
… and prioritized based on expression in fetal kidney, minor allele frequency less than 1%, and the predicted functional significance of the alteration on protein structure. Candidate mutations were then assessed in each family for cosegregation with the affected/obligate carrier status. …
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Indagini strutturali e quantitative durante lo sviluppo del rene mediante l’utilizzo di elaborazione immagini
… A very relevant aspect is the development of the kidney. Nephron number at birth has a relevant clinical importance with implications for long-term renal health. In recent years, the podocyte depletion hypothesis has emerged as an important concept in kidney pathology. Moreover, a variety of renal …