Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"female germ cells"”.
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The role of beta-catenin in the development of fetal ovary and female germ cells
… ovarian development, 2) identify the causes of female germ cell loss in the absence of WNT4/β-catenin signaling pathway, and 3) investigate the molecular connection between Wnt4 and β-catenin. In the first study of determining the functional roles of β-catenin, I generated a transgenic mouse …
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Dazl regulates mouse embryonic germ cell development
In the mouse, germ cells can undergo differentiation to become either oocytes or spermatozoa in response to sex of their gonadal environment. The nature of the germ cell-intrinsic aspects of this signaling have not been well studied. The earliest known sex-specific difference in germ cells is the …
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Germ cell nuclear factor is not required for the down-regulation of pluripotency markers in fetal ovarian germ cells
In mouse, germ cells retain expression of the pluripotency markers Oct4 and Nanog longer than any other cells in the body. While somatic cells repress these markers during gastrulation, female germ cells continue to express them until around the time of meiotic initiation. It is not yet clear why …
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Sexual differentiation of somatic and germ cell lineages of the mouse gonad
… the sex differentiation and meiotic entry of female germ cells occurs in an anterior-to-posterior wave. The presence of this wave indicates that local environmental cues in the ovary may regulate meiotic entry.
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Rbfox1 Regulates mRNA Translation to Promote Germ Cell Differentiation
Germ cells are the only cells that can give rise to an embryo. During differentiation, female germ cells that will give rise to oocytes form a syncytium called a germline cyst. The mechanisms that regulate germline cyst development remain poorly understood. In Drosophila, germline stem cells (GSCs) …
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Toxicity of TCDD in the mouse antral follicle
… shown to have effects on ovarian tissues and cells in culture and to encompass environmentally relevant and pharmacological exposures (0.1-100nM). The results indicate that TCDD decreases progesterone (P), androstenedione (A4), testosterone (T), and estradiol (E2) levels in a dose response …