Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"favipiravir"”.
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Human Parainfluenza Virus 3: Genetic Diversity, Virulence and Antiviral Susceptibility
… three potential inhibitors of HPIV3: ribavirin, favipiravir and zanamivir. The results showed that clinical strains were at least as susceptible to ribavirin and favipiravir as the laboratory reference strain and significantly more susceptible to zanamivir. This indicates that further work on …
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The use of insect cells to identify potent and selective inhibitors of the replication of the Dengue and Chikungunya viruses and unravel their molecular mechanism of action
… of the DENV life cycle, was selected. Finally, Favipiravir or T-705, was identified as inhibitor in vitro and in vivo of alphaviruses and the mutation K291R in nsP4, which is responsible of the polymerase activity, was found as the mode of action in CHIKV. Interestingly, lysine in motif F1 is …
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The physical origins of specimen movement in electron cryomicroscopy and how to eliminate it
… polymerase in presence of RNA and the inhibitor favipiravir, (2) the light-harvesting 2 antenna complex of the purple bacterium Mch. purpuratum, and (3) the double-ring photosystem of G. phototrophica. These examples illustrate how movement-free imaging allowed us to better visualise ligand …