Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"fatty acid desaturase"”.
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Genomic Organization of Fatty Acid Desaturase-2 (Fad2 ) and Fatty Acid Desaturase-6 (Fad6) ESTs in Maize
… palmitic, stearic, oleic, linoleic and linolenic fatty acids. Increased levels of oleic acid may enhance the nutritional and functional value of corn oil. The biochemical pathway for fatty acid biosynthesis indicates that a single enzyme, the delta12 desaturase, converts oleic (18: 1) to linoleic …
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Isolation and analysis of cotton genomic clones encompassing a fatty acid desaturase (FAD2) gene
Polyunsaturated fatty acids are major structural components of plant chloroplast and endoplasmic reticulum membranes. Two fatty acid desaturases (designated FAD2 and FAD3) desaturate 75% of the fatty acids in the endoplasmic reticulum. The w -6 fatty acid desaturase (FAD2) may be responsible for …
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Influence of Loss of Function of the Fatty Acid Desaturase 7 Gene on Photosynthetic Activity and Foliar Redox Status
<p>Fatty Acid Desaturase7 (FAD7) is a chloroplast-localized enzyme that converts 16 and 18 carbon dienoic fatty acids to trienoic fatty acids. The suppressor of prosystemin-mediated response2 (spr2) mutant in tomato (Solanum lycopersicum) and the fad7-1 mutant in Arabidopsis (Arabidopsis thaliana) …
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Impact of fatty acid desaturase (FADS) genotypes on the relationship between serum lipids and dietary fat intake in young Mexican college students
Made available in DSpace on 2014-09-16T17:11:50Z (GMT). No. of bitstreams: 2 Itzel_Vazquez Vidal.pdf: 1981856 bytes, checksum: c424238f3b6a362ce0b880e86b24c857 (MD5) license.txt: 4069 bytes, checksum: cf44c5f7be9fd4ce7fb4f5d85a48bc3c (MD5)
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Molecular cloning and analysis of the genes for cotton palmitoyl-acyl carrier protein thioesterase (PATE) and Δ-12 fatty acid desaturase (FAD2-3) and construction of sense and anti-sense PATE plasmid vectors for altering oilseed composition of transgenic cotton plants.
… insert with an coding region for 410 amino acids, lacking codons for the three N-terminal amino acids. The predicted amino acid sequence of the PATE preprotein has a characteristic stromal-targeting domain and a 63% identity to the Arabidopsis FatB1 thioesterase sequence. A cotton genomic …
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Isoflurane : interaction with hepatic microsomal enzymes
… and human hepatic microsomes and the Δ6- and Δ5-desaturases in rat hepatic microsomes. The interaction of isoflurane with cytochrome P-450 results in its metabolism to fluoride ion and organofluorine metabolites. The cytochrome P-450 isozymes catalysing the defluorination of isoflurane were …
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Validation and Application of a Novel Target-Based Whole-Cell Screen to Identify Antifungal Compounds
… fungal infections.</p> <p>Both the fungal fatty acid synthase and desaturase have been established as essential for fungal growth, virulence in a systemic infection, and are structurally distinct from their mammalian counterparts. However, there has been little success in developing …
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THE ROLE OF BOTANICAL OILS ENRICHED IN FADS2-DERIVED N-3 VS. N-6 POLYUNSATURATED FATTY ACIDS IN PREVENTION OF ATHEROSCLEROSIS
Background: Dietary polyunsaturated fatty acids (PUFAs) reduce atherosclerosis in animal models and humans relative to dietary saturated and monounsaturated fatty acids. Although some of the atheroprotection of dietary PUFAs is due to plasma lipid lowering, in vivo conversion of 18 carbon PUFAs …
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FADS2 expression modulates effect of dietary polyunsaturated fatty acids on western diet-induced glucose intolerance
Fatty Acid Desaturase 2 (FADS2) haplotypes associated with hyperactivity of its gene product, delta-6-desaturase (D6D), are associated with obesity and type-2 diabetes in humans. D6D regulates long-chain polyunsaturated fatty acid (PUFA) biosynthesis and is upregulated in several rodent models of …
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Biomarkers of fat intake
… thesis reviews the previous use of biomarkers of fatty acid intake and concludes that there is a lack of supporting evidence from large randomized controlled trials (RCT) of sufficient duration for their use to be justified. The hypothesis that fatty acid biomarkers are robust indices of the …
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Investigating the Relation Between Genetic Variation in FADS1 & FADS2 with the LCPUFA Content of Extracellular Vesicles from Human Milk
… the concentrations of long-chain polyunsaturated fatty acids (LCPUFA) in human milk EVs. As integral components of the lipid membrane, the specific composition or balance of LCPUFAs may impact the bioavailability of EVs in newborns consuming human milk. The objective of this study was to determine …
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Interaction between dietary factors and genetic risk for lipoprotein traits and cardiovascular disease
… diet components, such as polyunsaturated fatty acids (PUFAs), have been hypothesized to reduce the risk of CVD. However, results from epidemiological studies have been conflicting. This may be due to individuals having varied genetic profiles that are differentially associated with CVD. In …
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The effects of whole-diet interactions on vascular health and inflammatory and fatty acid status.
… (including advice on intakes of the n-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)) on chronic low grade inflammation (primary end-point) in 1250 older adults (aged 65-79 years) in five EU centres. As part of this thesis, the impact of intervention on vascular …
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Global transcriptional, post-transcriptional, and translational regulation during soybean seed and seedling development
… genes include AP2 transcription factor, fatty acid desaturase and WRKY transcription factor. Additionally, DNA binding motifs were identified for the NAC and YABBY transcription factors. Post-transcriptional regulation is another layer of gene regulation. In order to dissect miRNA guided …
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Post-translational Regulation of Plant Fatty Acid Desaturases as Expressed in Saccharomyces cerevisiae
… element. I attempted to determine specific amino acids important for regulation, and further characterize the mechanism contributing to the differences. Through site-directed mutagenesis, it was shown that replacing lysine residues with asparagines in the BF3 and TF3 Ntermini increased protein …