Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"farnesylpyrophosphate"”.
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HMG-CoA Reductase Inhibitors Act Synergistically with UCN-01 Through RAS Inhibition
… formation of geranylgeranylpyrophosphate and farnesylpyrophosphate by interfering with the rate-limiting step of the mevalonate pathway. Geranylgeranylpyrophosphate and farnesylpyrophosphate induce post-translational modifications in RAS that anchor the protein to the cell membrane so that it …
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Wpływ bisfosfonianów stosowanych w terapii osteoporozy na metabolizm tlenowy komórek śródbłonka
… action of N-BPs is based on blocking the enzyme farnesylpyrophosphate synthase (FPPS) in the mevalonate pathway. The mevalonate pathway plays an important role in many cellular processes such as protein prenylation and post-translational modifications as well as the synthesis of molecules …