Global ETD Search
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Showing 1 to 16 of 16 for “"facilitated diffusion"”.
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Facilitated diffusion in rabbit erythrocytes
<p>The present kinetic study of the permeability of rabbit erythrocytes has established that carrier systems are involved in the penetration of certain non-electrolytes. Saturation, competitive inhibition, and butanol inhibition kinetics were used to demonstrate the presence of carrier systems and …
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Simple and facilitated diffusion in rat erythrocytes
<p>Early studies of the permeability of the animal cell membrane were difficult to compare, because of the variety of cell types involved. In the late nineteenth century, workers chose to use erythrocytes due to their advantages over using a variety of cell types. With erythrocytes a comparison …
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Glycerol permeability in erythrocytes of Peromyscus californicus : the effect of temperature
… (ø) and the maximum transport rate (K) of the facilitated diffusion of glycerol across the erythrocyte membrane of Peromyscus californicus.
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Modelling transcription factors diffusion in 3D using Hi-C data
… to it. In the search mechanism also known as facilitated diffusion, TFs can float freely (Brownian motion) in the nucleoplasm and can bind to non-specific sites performing one- dimensional walks along the DNA strand. Once bound, TFs can slide, hop, or jump across. Recent technological …
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Theoretical investigation of protein search for targets on DNA
… on DNA much faster than expected from 3D bulk diffusional estimates which follow from the famous theory developed by M.Smoluchovski. This phenomenon is known as facilitated diffusion. After extensive investigation via theoretical and experimental methods, it has been argued that the facilitated …
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Mechanisms of biochemical reactions within crowded environments
… to study the effects of molecular crowding on facilitated diffusion. We find that obstacles on the DNA impair facilitated diffusion. However, the extent of this effect depends on how dynamic obstacles are on the DNA. For the scenario in which crowders are only present in the bulk solution, we …
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Glycerol permeability in two species of Peromyscus
… did not enter the human red cell by simple diffusion, but rather that these penetrants were transported into the erythrocyte by an active metabolic system in which at least one essential link involved a sulfhydryl group</p>Jacobs, et al. (1950) examined the inter-class erythrocyte …
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Visualizing the One-Dimensional Diffusion of DNA Mismatch Repair Proteins at the Single-Molecule Level
… in this work also reveal distinct mechanisms of diffusion utilized by each complex. The observed diffusive behavior of Msh2-Msh6 is consistent with a model in which the protein forms a highly processive clamp that rotates about the DNA helical axis as it diffuses, thereby remaining in register …
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ΜΕΛΕΤΗ ΕΝΔΟΚΥΤΤΑΡΙΟΥ ΦΩΣΦΟΡΟΥ ΣΕ ΠΡΟΩΡΑ ΝΕΟΓΝΑ ΚΑΤΑ ΤΟΥΣ ΔΥΟ ΠΡΩΤΟΥΣ ΜΗΝΕΣ ΤΗΣ ΖΩΗΣ ΤΟΥΣ
… OF PI TRANSPORT ACROSS THE MEMBRANE THAN FACILITATED DIFFUSION. THE PHYSIOLOGICAL DECREASE IN RED CELL HAEMOGLOMBIN CALCULATED FROM HAEMATOCRIT WAS NEGATIVELY RELATED TO THE INCREASE IN RED CELL PHOSPHATE. IT PROBABLY INDICATES A ROLE OF THIS HIGHLY CHARGED PROTEIN AFFECTING THE ANION …
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Control of glucose and xylose utilization by Clostridium thermohydrosulfuricum Rt8.B1
… uptake and the kinetics were indicative of facilitated diffusion. The xylose isomerase of Cl. thermohydrosulfuricum Rt8.B1 had a high Kₘ for xylose (low-affinity) and xylulokinase had a low Kₘ for xylose (high-affinity). The Kₘ for xylulokinase was lower than the Kₜ for the high-affinity …
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Utilization of L( - )-glucose by naturally occuring microorganisms
… L-glucose. L-glucose transport takes place by facilitated diffusion at V[subscript max] = 2.63 x 10⁻³ mg L-glucose/(mg cells-min) and K[subscript m]= 0.65 g/L L-glucose. The organism probably utilizes the entire L-glucose molecule. There is evidence that carbon 1 is eliminated as CO₂ and …
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Flavonoids and Related Compounds as Nucleoside Transporter Inhibitors
… and mediate sodium-independent bi-directional facilitated diffusion nucleoside transport processes. CNTs on the other hand, are secondary active unidirectional transporters that are sodium-dependent. Both the equilibrative and the concentrative nucleoside transporters have several family …
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Study and engineering of nucleic acid-binding repeat proteins
… For the first time, the binding dynamics and 1-D diffusion of TALE proteins along DNA were directly visualized. The data strongly suggest that TALE searches its target using the facilitated diffusion mechanism, with a combination of 1-D and 3-D diffusion before it reaches its target sequence. This …
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Mammalian genome engineering: Fundamental investigation and method development
… results show that TALEs display heterogeneous diffusion behaviors. On further elucidation of the slow diffusion molecules, we discover evidence for local search in the genome. Overall, TALEs undergo facilitated diffusion in the crowded nucleoplasm of a live HeLa cell. In Chapter 3, I performed …
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The effects of adjuvents upon the pesticide uptake and penetration of foliage
… in both partition coefficient and (estimated) diffusion coefficient. The distribution of oligomers within anyone surfactant was apparently retained during transcuticular movement. Movement of the surfactant across the epicuticular waxes resulted in an accumulation of the penetrant in the …
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Mode of action of organosilicone surfactants in enhancing the performance of Triclopyr herbicide
… believed to apply in this situation because of a facilitated diffusion process occurring either in the uptake of triclopyr through the cuticle and/or in the loading of cells across membranes, such as into the phloem. A closer examination of uptake during the first 2 h suggested a two phase model …